Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.0723 | 0.0723 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0129 | 0.0666 | 1 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0164 | 0.0947 | 0.0947 |
Giardia lamblia | Kinase, CMGC CDK | 0.0047 | 0 | 0.5 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0164 | 0.0947 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0129 | 0.0666 | 0.0666 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0129 | 0.0666 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/JNK protein kinase | 0.0233 | 0.1506 | 0.1506 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0164 | 0.0947 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0047 | 0 | 0.5 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0164 | 0.0947 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0129 | 0.0666 | 0.0666 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0164 | 0.0947 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0129 | 0.0666 | 0.0666 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0129 | 0.0666 | 0.0666 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0129 | 0.0666 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1281 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0 | 0.5 |
Echinococcus multilocularis | c Jun NH2 terminal kinase | 0.0233 | 0.1506 | 0.1506 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0129 | 0.0666 | 0.0666 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0129 | 0.0666 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0047 | 0 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0129 | 0.0666 | 0.0666 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0047 | 0 | 0.5 |
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.1281 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0129 | 0.0666 | 0.0666 |
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.1281 | 1 | 1 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0164 | 0.0947 | 0.0947 |
Brugia malayi | P38 map kinase family protein 2 | 0.0129 | 0.0666 | 0.0666 |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.1281 | 1 | 1 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0164 | 0.0947 | 0.0947 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0233 | 0.1506 | 0.1506 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0164 | 0.0947 | 0.0947 |
Brugia malayi | diacylglycerol acyltransferase | 0.0164 | 0.0947 | 0.0947 |
Echinococcus granulosus | c-Jun N-terminal kinases | 0.0233 | 0.1506 | 0.1506 |
Brugia malayi | Stress-activated protein kinase jnk-1 | 0.0233 | 0.1506 | 0.1506 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0047 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.