Detailed information for compound 941994

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 453.594 | Formula: C26H31NO4S
  • H donors: 2 H acceptors: 4 LogP: 5.24 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCC/C=C\C[C@H]1[C@@H]2CCC([C@@H]1NS(=O)(=O)c1ccc(cc1)c1ccccc1)C2
  • InChi: 1S/C26H31NO4S/c28-25(29)11-7-2-1-6-10-24-21-12-13-22(18-21)26(24)27-32(30,31)23-16-14-20(15-17-23)19-8-4-3-5-9-19/h1,3-6,8-9,14-17,21-22,24,26-27H,2,7,10-13,18H2,(H,28,29)/b6-1-/t21-,22?,24+,26+/m1/s1
  • InChiKey: NKFFKDVJGSLYGD-IFVDKXSBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0362 0.2609 0.2731
Schistosoma mansoni jumonji domain containing protein 0.0086 0.0422 0.0789
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.028 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0185 0.0228
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0056 0.0185 0.0228
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0157 0.0157
Toxoplasma gondii hypothetical protein 0.0154 0.0958 1
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0056 0.0185 0.0346
Plasmodium vivax hypothetical protein, conserved 0.0121 0.0696 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0167 0.0313
Entamoeba histolytica kinesin, putative 0.0106 0.0574 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0418 0.3057 0.3057
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0089 0.0446 0.2319
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.2658
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Loa Loa (eye worm) hypothetical protein 0.0056 0.0185 0.0194
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0157 0.1635
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.2658
Plasmodium vivax phosphodiesterase gamma, putative 0.0056 0.0185 0.2658
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0157 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0177 0.1145 0.7909
Toxoplasma gondii GAF domain-containing protein 0.0121 0.0696 0.7272
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Loa Loa (eye worm) hypothetical protein 0.0418 0.3057 0.32
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0056 0.0185 0.0185
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Plasmodium falciparum phosphodiesterase gamma, putative 0.0056 0.0185 0.2658
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0054 0.0167 0.0167
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0103 0.0103
Brugia malayi Kinesin motor domain containing protein 0.0106 0.0574 0.0574
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Plasmodium falciparum GAF domain-related protein, putative 0.0121 0.0696 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0056 0.0185 0.0228
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Loa Loa (eye worm) hypothetical protein 0.0056 0.0185 0.0194
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.021 0.1406 0.1406
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0056 0.0185 0.0228
Brugia malayi jmjC domain containing protein 0.0109 0.0599 0.0599
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0089 0.0446 0.2319
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.2658
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0387 0.2805 0.5246
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0056 0.0185 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0185 0.0228
Onchocerca volvulus Alhambra homolog 0.0033 0 0.5
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.021 0.1406 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0167 0.0167
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0235 0.0235
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0157 0.0164
Schistosoma mansoni lipoxygenase 0.0063 0.0235 0.044
Schistosoma mansoni hypothetical protein 0.0707 0.5347 1
Mycobacterium ulcerans putative regulatory protein 0.0121 0.0696 0.5
Loa Loa (eye worm) hypothetical protein 0.0177 0.1145 0.1199
Trichomonas vaginalis conserved hypothetical protein 0.021 0.1406 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0054 0.0167 0.0175
Brugia malayi MAP kinase sur-1 0.0053 0.0157 0.0157
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0056 0.0185 0.0194
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0055 0.0104
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0024 0.0024
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0109 0.0599 0.0599
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0056 0.0185 0.2658
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0056 0.0185 0.0185
Trypanosoma brucei hypothetical protein, conserved 0.0056 0.0185 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0696 0.4321
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Toxoplasma gondii hypothetical protein 0.0121 0.0696 0.7272
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Plasmodium falciparum kinesin-5 0.0106 0.0574 0.8248
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Loa Loa (eye worm) PDE1B protein 0.0056 0.0185 0.0194
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.2658
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0056 0.0185 0.0185
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Plasmodium vivax kinesin-5 0.0106 0.0574 0.8248
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0055 0.0104
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0121 0.0696 0.5
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0056 0.0185 0.0185
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0056 0.0185 0.0185
Mycobacterium ulcerans putative regulatory protein 0.0121 0.0696 0.5
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0056 0.0185 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0056 0.0185 0.0185
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0121 0.0696 0.5
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0056 0.0185 0.0228
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0177 0.1145 0.2141
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0056 0.0185 0.0185
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0157 0.0157
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.021 0.1406 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0185 0.0228
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0056 0.0185 0.0185
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.1713 0.1794
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0167 0.0313
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0056 0.0185 0.0228
Toxoplasma gondii hypothetical protein 0.0121 0.0696 0.7272
Echinococcus multilocularis muscleblind protein 0.015 0.0928 0.0928
Brugia malayi Cytochrome P450 family protein 0.0035 0.0012 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0056 0.0185 0.3223
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0056 0.0185 0.0185
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0109 0.0599 0.0599
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0012 0.0013
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.007 0.0295 0.0551
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0121 0.0696 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0167 0.0167
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.021 0.1406 0.2629
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Brugia malayi Muscleblind-like protein 0.015 0.0928 0.0928
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.021 0.1406 1
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0056 0.0185 0.0346
Leishmania major cAMP-specific phosphodiesterase, putative 0.0056 0.0185 0.0228
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Brugia malayi hypothetical protein 0.0036 0.0024 0.0024
Echinococcus granulosus muscleblind protein 0.015 0.0928 0.0928
Schistosoma mansoni hypothetical protein 0.0036 0.0024 0.0044
Trypanosoma brucei cAMP-specific phosphodiesterase 0.021 0.1406 1
Echinococcus multilocularis muscleblind protein 1 0.015 0.0928 0.0928
Brugia malayi jmjC domain containing protein 0.004 0.0055 0.0055
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.021 0.1406 0.1406
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Leishmania major hypothetical protein, conserved 0.0056 0.0185 0.0228
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0177 0.1145 0.7909
Giardia lamblia hypothetical protein 0.0056 0.0185 0.3223
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.1293 1 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0056 0.0185 0.0185
Plasmodium falciparum phosphodiesterase delta, putative 0.0056 0.0185 0.2658
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0056 0.0185 0.0185
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Echinococcus multilocularis kinesin family 1 0.0813 0.6185 0.6185
Loa Loa (eye worm) hypothetical protein 0.015 0.0928 0.0972
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0958 0.6412
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0103 0.0103
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0177 0.1145 0.7909
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Loa Loa (eye worm) hypothetical protein 0.015 0.0928 0.0972
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0089 0.0446 0.2319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0167 0.0313
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0167 0.0167
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0055 0.0055
Trypanosoma brucei cAMP-specific phosphodiesterase 0.021 0.1406 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0056 0.0185 0.0185
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0055 0.0055
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0056 0.0185 0.1933
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0055 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0167 0.0167
Mycobacterium leprae conserved hypothetical protein 0.0121 0.0696 0.5
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0056 0.0185 0.0228
Giardia lamblia Hypothetical protein 0.0056 0.0185 0.3223
Loa Loa (eye worm) kinesin-like protein KLP2 0.0106 0.0574 0.0601
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0157 0.0157
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.021 0.1406 1
Echinococcus granulosus microtubule associated protein 2 0.0694 0.5242 0.5242
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0056 0.0185 0.0228
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0235 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0958 0.6412
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Echinococcus granulosus kinesin family 1 0.0813 0.6185 0.6185
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Toxoplasma gondii kinesin motor domain-containing protein 0.0106 0.0574 0.5998
Loa Loa (eye worm) hypothetical protein 0.1237 0.9552 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Giardia lamblia Kinesin-5 0.0106 0.0574 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.021 0.1406 1
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0056 0.0185 0.2658
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0177 0.1145 0.1145
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.021 0.1406 1
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0056 0.0185 0.0185
Schistosoma mansoni kinesin eg-5 0.0106 0.0574 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0157 0.0293
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.0228
Leishmania major hypothetical protein, conserved 0.0056 0.0185 0.0228
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.5242 0.5242
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.1293 1 1
Loa Loa (eye worm) hypothetical protein 0.1116 0.8592 0.8995
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0958 0.6412
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0157 0.2726
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0056 0.0185 0.0346
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0024 0.0044
Brugia malayi follicle stimulating hormone receptor 0.0249 0.1713 0.1713
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0056 0.0185 0.0185
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0056 0.0185 0.2658
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.5242 0.9803
Loa Loa (eye worm) hypothetical protein 0.0057 0.0188 0.0197

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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