Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.1214 | 0.1214 |
Echinococcus granulosus | cysteine protease | 0.0016 | 0.0386 | 0.0386 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.3173 | 0.3173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0452 | 0.0452 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0019 | 0.065 | 0.0274 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0019 | 0.065 | 0.065 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.3173 | 0.3173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0049 | 0.297 | 1 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.1214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0452 | 0.0452 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1914 | 0.1914 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.3173 | 0.3173 |
Onchocerca volvulus | 0.0019 | 0.065 | 0.5353 | |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0049 | 0.297 | 0.297 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0049 | 0.297 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.014 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0452 | 0.0452 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0026 | 0.1214 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0026 | 0.1214 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0026 | 0.1214 | 1 |
Echinococcus granulosus | cathepsin b | 0.014 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.065 | 0.1018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0049 | 0.297 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0452 | 0.0452 |
Echinococcus granulosus | cathepsin b | 0.014 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.1214 | 1 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0026 | 0.1214 | 0.1214 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | fibroinase | 0.0026 | 0.1214 | 0.1214 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.1214 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0026 | 0.1214 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1214 | 0.1214 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0026 | 0.1214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1914 | 0.1914 |
Brugia malayi | cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.065 | 0.065 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.3173 | 0.3173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.1214 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.1214 | 0.1214 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.065 | 0.3182 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Echinococcus granulosus | cathepsin L | 0.0016 | 0.0386 | 0.0386 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0452 | 0.0452 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.065 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0452 | 0.0452 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.014 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.014 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus multilocularis | cathepsin L | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1914 | 0.1914 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0016 | 0.0386 | 0.0386 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.1214 | 0.1214 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0049 | 0.297 | 0.2688 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.065 | 0.065 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Echinococcus multilocularis | cathepsin b | 0.014 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0386 | 0.0386 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0049 | 0.297 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.1214 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.1214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | ctsf protein | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0026 | 0.1214 | 0.086 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Loa Loa (eye worm) | cathepsin B | 0.0049 | 0.297 | 0.297 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.