Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.065 | 0.065 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1914 | 0.1914 |
Brugia malayi | cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0026 | 0.1214 | 0.1214 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0026 | 0.1214 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0026 | 0.1214 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.065 | 0.1018 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Echinococcus granulosus | cathepsin L | 0.0016 | 0.0386 | 0.0386 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0452 | 0.0452 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.065 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.1214 | 0.1214 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Loa Loa (eye worm) | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.1214 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.3173 | 0.3173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Toxoplasma gondii | cathepsin B | 0.0049 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.014 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0386 | 0.0386 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.1214 | 0.1214 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.065 | 0.065 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0049 | 0.297 | 0.2688 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.1214 | 0.1214 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1914 | 0.1914 |
Echinococcus multilocularis | cathepsin L | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.065 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Echinococcus multilocularis | cathepsin b | 0.014 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.014 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | cathepsin B | 0.0049 | 0.297 | 0.297 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0026 | 0.1214 | 0.086 |
Loa Loa (eye worm) | ctsf protein | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.1214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.1214 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0049 | 0.297 | 1 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.1214 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.3173 | 0.3173 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0019 | 0.065 | 0.065 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0019 | 0.065 | 0.0274 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0452 | 0.0452 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.3173 | 0.3173 |
Echinococcus granulosus | cysteine protease | 0.0016 | 0.0386 | 0.0386 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0049 | 0.297 | 0.297 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0049 | 0.297 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | 0.0019 | 0.065 | 0.5353 | |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.3173 | 0.3173 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1914 | 0.1914 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0452 | 0.0452 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.1214 | 0.086 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.1214 | 0.1214 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.014 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.1214 | 0.1214 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0452 | 0.0452 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0452 | 0.0452 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0049 | 0.297 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.065 | 0.1018 |
Echinococcus granulosus | cathepsin b | 0.014 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0026 | 0.1214 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0026 | 0.1214 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.014 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0452 | 0.0452 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0026 | 0.1214 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.1214 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | fibroinase | 0.0026 | 0.1214 | 0.1214 |
Giardia lamblia | Cathepsin B precursor | 0.0049 | 0.297 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0386 | 0.0386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0026 | 0.1214 | 0.1214 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.065 | 0.065 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.1214 | 0.1214 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.014 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0026 | 0.1214 | 0.3201 |
Onchocerca volvulus | 0.0026 | 0.1214 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.1214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.1214 | 0.3201 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.