Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | lysine-specific permease, putative | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Mycobacterium ulcerans | GabA permease GabP | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Mycobacterium leprae | POSSIBLE L-ASPARAGINE PERMEASE ANSP1 (L-ASPARAGINE TRANSPORT PROTEIN) | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Mycobacterium ulcerans | L-asparagine permease AnsP1 | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Trichomonas vaginalis | gaba permease, putative | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.1527 | 1 | 1 |
Mycobacterium tuberculosis | Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease) | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible L-asparagine permease AnsP2 (L-asparagine transport protein) | 0.0201 | 0 | 0.5 |
Brugia malayi | Hypothetical 112.3 kDa protein K02A2.3 in chromosome II | 0.1413 | 0.9143 | 0.9143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Brugia malayi | Amino acid permease family protein | 0.1413 | 0.9143 | 0.9143 |
Mycobacterium ulcerans | D-serine/D-alanine/glycine transporter, CycA | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | cation chloride cotransporter, putative | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Schistosoma mansoni | solute carrier family 12 electroneutral k-cl cotransporter | 0.1413 | 0.9143 | 1 |
Mycobacterium tuberculosis | Probable D-serine/alanine/glycine transporter protein CycA | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | cation chloride cotransporter, putative | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1413 | 0.9143 | 0.9143 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Trichomonas vaginalis | amino acid permease, putative | 0.0201 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1212 | 0.7626 | 0.7626 |
Echinococcus granulosus | solute carrier family 12 | 0.1413 | 0.9143 | 1 |
Trichomonas vaginalis | aromatic amino acid transporter, putative | 0.0201 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 12 | 0.1413 | 0.9143 | 1 |
Loa Loa (eye worm) | amino acid permease | 0.1413 | 0.9143 | 0.9143 |
Mycobacterium leprae | POSSIBLE L-ASPARAGINE PERMEASE ANSP2 (L-ASPARAGINE TRANSPORT PROTEIN) | 0.0201 | 0 | 0.5 |
Onchocerca volvulus | Solute carrier family 12 member 9 homolog | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0201 | 0 | 0.5 |
Onchocerca volvulus | Solute carrier family 12 member 8 homolog | 0.0201 | 0 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 17190455 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.