Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0295 | 0.0295 |
Brugia malayi | solute carrier family 12 member 1 | 0.0109 | 0.0295 | 0.0295 |
Mycobacterium tuberculosis | Possible L-asparagine permease AnsP2 (L-asparagine transport protein) | 0.0109 | 0.0295 | 0.5 |
Brugia malayi | Amino acid permease family protein | 0.0109 | 0.0295 | 0.0295 |
Loa Loa (eye worm) | solute carrier family 12 member 1 | 0.0109 | 0.0295 | 0.0295 |
Trichomonas vaginalis | amino acid permease, putative | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | amino acid permease | 0.0763 | 0.2617 | 0.2617 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Trichomonas vaginalis | cation chloride cotransporter, putative | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Mycobacterium ulcerans | L-asparagine permease AnsP1 | 0.0109 | 0.0295 | 0.5 |
Schistosoma mansoni | solute carrier family 12 electroneutral k-cl cotransporter | 0.0763 | 0.2617 | 1 |
Onchocerca volvulus | Solute carrier family 12 member 8 homolog | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Trichomonas vaginalis | lysine-specific permease, putative | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Trichomonas vaginalis | gaba permease, putative | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Brugia malayi | hypothetical protein | 0.0109 | 0.0295 | 0.0295 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Mycobacterium leprae | POSSIBLE L-ASPARAGINE PERMEASE ANSP2 (L-ASPARAGINE TRANSPORT PROTEIN) | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Mycobacterium ulcerans | GabA permease GabP | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Onchocerca volvulus | Solute carrier family 12 member 9 homolog | 0.0109 | 0.0295 | 0.5 |
Mycobacterium ulcerans | D-serine/D-alanine/glycine transporter, CycA | 0.0109 | 0.0295 | 0.5 |
Echinococcus multilocularis | solute carrier family 12 | 0.0763 | 0.2617 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Mycobacterium tuberculosis | Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease) | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Brugia malayi | Hypothetical 112.3 kDa protein K02A2.3 in chromosome II | 0.0763 | 0.2617 | 0.2617 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.2843 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0295 | 0.0295 |
Mycobacterium tuberculosis | Probable D-serine/alanine/glycine transporter protein CycA | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Mycobacterium leprae | POSSIBLE L-ASPARAGINE PERMEASE ANSP1 (L-ASPARAGINE TRANSPORT PROTEIN) | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0763 | 0.2617 | 0.2617 |
Trichomonas vaginalis | cation chloride cotransporter, putative | 0.0109 | 0.0295 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0654 | 0.2232 | 0.2232 |
Trichomonas vaginalis | aromatic amino acid transporter, putative | 0.0109 | 0.0295 | 0.5 |
Brugia malayi | hypothetical protein | 0.0109 | 0.0295 | 0.0295 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.0295 | 0.5 |
Echinococcus granulosus | solute carrier family 12 | 0.0763 | 0.2617 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0295 | 0.0295 |
Brugia malayi | Amino acid permease family protein | 0.0763 | 0.2617 | 0.2617 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.