Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.004 | 0 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0756 | 0.0756 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0047 | 0.0496 | 0.1015 |
Trypanosoma brucei | glucosidase, putative | 0.004 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0109 | 0.4892 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0109 | 0.4892 | 0.4892 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0109 | 0.4892 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0181 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0181 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Schistosoma mansoni | alpha-glucosidase | 0.0156 | 0.821 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0181 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0109 | 0.4892 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0109 | 0.4892 | 0.4892 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0756 | 0.0756 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0181 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0756 | 0.0756 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0109 | 0.4892 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0109 | 0.4892 | 0.5959 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Schistosoma mansoni | glycogen phosphorylase | 0.0047 | 0.0496 | 0.0605 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0756 | 0.0756 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0047 | 0.0496 | 0.1015 |
Schistosoma mansoni | alpha-glucosidase | 0.0156 | 0.821 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0756 | 0.0756 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0047 | 0.0496 | 0.1015 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0047 | 0.0496 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0047 | 0.0496 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0756 | 0.0921 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0109 | 0.4892 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0109 | 0.4892 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0109 | 0.4892 | 0.5959 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0109 | 0.4892 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0756 | 0.0756 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0 | 0.5 |
Leishmania major | alpha glucosidase II subunit, putative | 0.004 | 0 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.0109 | 0.4892 | 0.4892 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.