Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0246 | 0.5048 | 0.5048 |
Brugia malayi | hypothetical protein | 0.0144 | 0.2501 | 0.2501 |
Plasmodium falciparum | peptidase, putative | 0.0044 | 0 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0246 | 0.5048 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0443 | 1 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0246 | 0.5048 | 0.5048 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0044 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0044 | 0 | 0.5 |
Onchocerca volvulus | 0.0081 | 0.0925 | 0.0925 | |
Entamoeba histolytica | hypothetical protein, conserved | 0.0044 | 0 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0246 | 0.5048 | 0.5048 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0374 | 0.0374 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0044 | 0 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0246 | 0.5048 | 0.5048 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0081 | 0.0925 | 0.0925 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0189 | 0.3616 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0246 | 0.5048 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0044 | 0 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0784 | 0.0784 |
Brugia malayi | Cation transporter family protein | 0.0081 | 0.0925 | 0.0925 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0443 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0925 | 0.0925 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0246 | 0.5048 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0443 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.1432 | 0.1432 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0246 | 0.5048 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0443 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0 | 0.5 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0081 | 0.0925 | 0.0925 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0246 | 0.5048 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.4757 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0443 | 1 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0044 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.2501 | 0.2501 |
Onchocerca volvulus | 0.0081 | 0.0925 | 0.0925 | |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0925 | 0.0925 |
Onchocerca volvulus | 0.0081 | 0.0925 | 0.0925 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0044 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.