Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.051 | 0.0109 | 0.0109 |
Toxoplasma gondii | ion channel protein | 0.0436 | 0 | 0.5 |
Plasmodium vivax | potassium channel, putative | 0.0436 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0436 | 0 | 0.5 |
Trypanosoma brucei | calcium/potassium channel (CAKC), putative | 0.0436 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0436 | 0 | 0.5 |
Plasmodium falciparum | potassium channel | 0.0436 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.7246 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.051 | 0.0109 | 0.0109 |
Leishmania major | ion transport protein-like protein | 0.0436 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.0436 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.7246 | 1 | 1 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0436 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0436 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0436 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.681 | 0.936 | 0.936 |
Trypanosoma cruzi | ion transport protein, putative | 0.0436 | 0 | 0.5 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.7246 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0436 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0436 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0436 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.051 | 0.0109 | 0.0109 |
Trypanosoma cruzi | ion transport protein, putative | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.7246 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Plasmodium vivax | potassium channel, putative | 0.0436 | 0 | 0.5 |
Trypanosoma cruzi | calcium-activated potassium channel, putative | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Schistosoma mansoni | twik family of potassium channels-related | 0.7246 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0436 | 0 | 0.5 |
Mycobacterium ulcerans | ion transport protein | 0.0436 | 0 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0436 | 0 | 0.5 |
Toxoplasma gondii | ion channel protein | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Mycobacterium ulcerans | transmembrane cation transporter | 0.0436 | 0 | 0.5 |
Onchocerca volvulus | 0.0436 | 0 | 0.5 | |
Leishmania major | potassium channel subunit-like protein | 0.0436 | 0 | 0.5 |
Plasmodium falciparum | potassium channel | 0.0436 | 0 | 0.5 |
Trypanosoma brucei | calcium-activated potassium channel, putative | 0.0436 | 0 | 0.5 |
Trypanosoma cruzi | calcium/potassium channel (CAKC), putative | 0.0436 | 0 | 0.5 |
Leishmania major | calcium/potassium channel (CAKC), putative | 0.0436 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.