Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0158769 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.0158769 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0015145 | 0.043942 | 0.043942 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039409 | 0.205461 | 0.205461 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0015145 | 0.043942 | 0.043942 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0039409 | 0.205461 | 0.205461 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0158769 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0054554 | 0.306276 | 0.306276 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0015145 | 0.043942 | 0.043942 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0039409 | 0.205461 | 0.205461 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Echinococcus multilocularis | serine threonine protein kinase | 0.00485132 | 0.266064 | 0.266064 |
Brugia malayi | Protein kinase c protein 2 | 0.00461945 | 0.250629 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0054554 | 0.306276 | 0.306276 |
Loa Loa (eye worm) | hypothetical protein | 0.00454499 | 0.245672 | 0.245672 |
Schistosoma mansoni | atypical protein kinase C | 0.00145846 | 0.0402118 | 0.0402118 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054554 | 0.306276 | 0.306276 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0158769 | 1 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0102365 | 0.624538 | 0.624538 |
Loa Loa (eye worm) | hypothetical protein | 0.0158769 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.00533612 | 0.298336 | 0.298336 |
Toxoplasma gondii | AGC kinase | 0.000854379 | 0 | 0.5 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.00432512 | 0.231037 | 0.231037 |
Brugia malayi | protein kinase C II. | 0.0015145 | 0.043942 | 0.175326 |
Loa Loa (eye worm) | hypothetical protein | 0.00591136 | 0.336628 | 0.336628 |
Echinococcus granulosus | protein kinase C gamma type | 0.00485132 | 0.266064 | 0.266064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0015145 | 0.043942 | 0.043942 |
Echinococcus multilocularis | protein kinase c iota type | 0.00145846 | 0.0402118 | 0.0402118 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054554 | 0.306276 | 0.306276 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.00401537 | 0.210417 | 0.210417 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0039409 | 0.205461 | 0.205461 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c iota type | 0.00145846 | 0.0402118 | 0.0402118 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Leishmania donovani | ChEMBL23 | 19091562 | |
Plasmodium falciparum | 19091562 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.