Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0158769 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054554 | 0.306276 | 0.306276 |
Loa Loa (eye worm) | hypothetical protein | 0.0158769 | 1 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0102365 | 0.624538 | 0.624538 |
Loa Loa (eye worm) | hypothetical protein | 0.00454499 | 0.245672 | 0.245672 |
Schistosoma mansoni | atypical protein kinase C | 0.00145846 | 0.0402118 | 0.0402118 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Brugia malayi | Protein kinase c protein 2 | 0.00461945 | 0.250629 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0054554 | 0.306276 | 0.306276 |
Echinococcus multilocularis | serine threonine protein kinase | 0.00485132 | 0.266064 | 0.266064 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0015145 | 0.043942 | 0.043942 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0054554 | 0.306276 | 0.306276 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0039409 | 0.205461 | 0.205461 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0158769 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0015145 | 0.043942 | 0.043942 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.0158769 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0015145 | 0.043942 | 0.043942 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0039409 | 0.205461 | 0.205461 |
Loa Loa (eye worm) | hypothetical protein | 0.0039409 | 0.205461 | 0.205461 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0158769 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.000854379 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c iota type | 0.00145846 | 0.0402118 | 0.0402118 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0039409 | 0.205461 | 0.205461 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.00401537 | 0.210417 | 0.210417 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054554 | 0.306276 | 0.306276 |
Echinococcus multilocularis | protein kinase c iota type | 0.00145846 | 0.0402118 | 0.0402118 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0015145 | 0.043942 | 0.043942 |
Echinococcus granulosus | protein kinase C gamma type | 0.00485132 | 0.266064 | 0.266064 |
Loa Loa (eye worm) | hypothetical protein | 0.00432512 | 0.231037 | 0.231037 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.00591136 | 0.336628 | 0.336628 |
Brugia malayi | protein kinase C II. | 0.0015145 | 0.043942 | 0.175326 |
Toxoplasma gondii | AGC kinase | 0.000854379 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.000854379 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.00533612 | 0.298336 | 0.298336 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | 19091562 | ||
Leishmania donovani | ChEMBL23 | 19091562 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.