Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glucose transporter 2A | 0.0035 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt1 | 0.0035 | 0 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0112 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0112 | 1 | 0.5 |
Trypanosoma cruzi | hexose transporter | 0.0035 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0112 | 1 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Leishmania major | glucose transporter, lmgt2 | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0112 | 1 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0112 | 1 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Plasmodium falciparum | hexose transporter | 0.0112 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0112 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 1 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0035 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter 1E | 0.0035 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0112 | 1 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0112 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0112 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 2 % | Activation of human estrogen receptor beta expressed in HEK293 cells at 10 uM beta-galactosidase reporter gene assay relative to 3,17-beta-estradiol | ChEMBL. | 18517258 |
Activity (binding) | = 14.8 % | Activation of human estrogen receptor alpha expressed in HEK293 cells at 10 uM by beta-galactosidase reporter gene assay relative to 3,17 beta-estradiol | ChEMBL. | 18517258 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.