Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0061 | 0.0061 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0142 | 0.1459 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.04 | 0.04 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0251 | 0.0477 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.04 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0291 | 0.3402 | 0.5 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.04 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0426 | 0.5165 | 0.9828 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.3138 | 0.5971 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.04 | 0.04 |
Echinococcus multilocularis | serotonin receptor | 0.027 | 0.3138 | 0.3138 |
Echinococcus granulosus | tumor protein p63 | 0.0389 | 0.4694 | 0.4694 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.0061 | 0.0117 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.3402 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.3163 | 0.6018 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0251 | 0.0477 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0564 | 0.0564 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.04 | 0.04 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0251 | 0.0477 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.04 | 0.0762 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0034 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.1459 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0844 | 0.1606 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.3138 | 0.5971 |
Trichomonas vaginalis | set domain proteins, putative | 0.0484 | 0.5933 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.013 | 0.013 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0564 | 0.0633 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0564 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0432 | 0.5256 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.0844 | 0.0844 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0046 | 0.0087 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0059 | 0.0372 | 0.0372 |
Onchocerca volvulus | 0.0077 | 0.0614 | 0.1035 | |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0358 | 0.4276 | 0.8137 |
Echinococcus multilocularis | tumor protein p63 | 0.0389 | 0.4694 | 0.4694 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.04 | 0.04 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.3402 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.027 | 0.3138 | 0.3138 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0795 | 1 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.04 | 0.04 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0426 | 0.5165 | 0.9828 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0059 | 0.0372 | 0.0372 |
Onchocerca volvulus | 0.0484 | 0.5933 | 1 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0251 | 0.0477 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0035 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 0.4276 | 0.8137 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0385 | 0.0733 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.0844 | 0.0844 |
Brugia malayi | jmjC domain containing protein | 0.0035 | 0.0061 | 0.0117 |
Onchocerca volvulus | 0.0057 | 0.0348 | 0.0586 | |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.1459 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.027 | 0.3138 | 0.3138 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0358 | 0.4276 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0564 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0252 | 0.048 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.013 | 0.013 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.04 | 0.04 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.1991 | 0.3789 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0046 | 0.0087 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.04 | 0.0762 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0795 | 1 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0589 | 0.0589 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0348 | 0.0348 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0046 | 0.0046 |
Onchocerca volvulus | 0.0061 | 0.04 | 0.0675 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0564 | 0.0564 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0272 | 0.3163 | 0.6018 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.3163 | 0.6018 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.027 | 0.3138 | 0.3138 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0035 | 0.0061 | 0.0061 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0564 | 0.0564 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0059 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0348 | 0.0662 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0358 | 0.4276 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0564 | 0.0564 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0272 | 0.3163 | 0.6018 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0291 | 0.3402 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0564 | 0.0633 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0371 | 0.0371 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0358 | 0.4276 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0059 | 0.0372 | 0.0708 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0059 | 0.0372 | 0.0708 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0564 | 0.1073 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.04 | 0.04 |
Brugia malayi | Dopamine receptor protein 1 | 0.0432 | 0.5256 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0034 | 0.0048 | 0.0048 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.