Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 1.4666 | 1 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 1.2606 | 0.7745 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.553 | 0 | 0.5 |
Mycobacterium ulcerans | alpha-L-fucosidase | 1.4666 | 1 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 1.2606 | 0.7745 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.553 | 0 | 0.5 |
Loa Loa (eye worm) | alpha-L-fucosidase | 1.2606 | 0.7745 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MEC (binding) | > 100 ug ml-1 | Inhibition of Staphylococcus aureus 1199B norA efflux pump by spectrophotometry | ChEMBL. | 20605275 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.