Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | alpha-L-fucosidase | 0.2716 | 1 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1024 | 0 | 0.5 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.2335 | 0.7745 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1024 | 0 | 0.5 |
Schistosoma mansoni | alpha-l-fucosidase | 0.2335 | 0.7745 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.2335 | 0.7745 | 0.5 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.2716 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antifungal activity against Escherichia coli ATCC 25922 at 200 ug/disk after 48 hrs by standard disk diffusion assay | ChEMBL. | 16441079 | |
Activity (functional) | Antifungal activity against Candida albicans ATCC 14053 at 200 ug/disk after 48 hrs by standard disk diffusion assay | ChEMBL. | 16441079 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.