Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0099 | 0.1598 | 0.1598 |
Chlamydia trachomatis | glutamine binding protein | 0.0255 | 0.6722 | 0.5 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0099 | 0.1598 | 0.4874 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0099 | 0.1598 | 1 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0099 | 0.1598 | 0.1598 |
Mycobacterium tuberculosis | Probable glutamine-binding lipoprotein GlnH (GLNBP) | 0.0255 | 0.6722 | 0.5 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0099 | 0.1598 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0354 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Leishmania major | extracellular receptor, putative | 0.0051 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor kainate | 0.0099 | 0.1598 | 0.4874 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Onchocerca volvulus | 0.0051 | 0 | 0.5 | |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0099 | 0.1598 | 0.1598 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.015 | 0.3278 | 0.3278 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0099 | 0.1598 | 0.1598 |
Onchocerca volvulus | 0.0051 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1598 | 0.4874 |
Echinococcus multilocularis | glutamate receptor 2 | 0.015 | 0.3278 | 0.3278 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0099 | 0.1598 | 0.1598 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0099 | 0.1598 | 0.1598 |
Schistosoma mansoni | glutamate receptor NMDA | 0.015 | 0.3278 | 1 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0099 | 0.1598 | 0.1598 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0255 | 0.6722 | 0.5 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.0099 | 0.1598 | 0.1598 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0099 | 0.1598 | 0.1598 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0255 | 0.6722 | 0.5 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.0099 | 0.1598 | 0.1598 |
Schistosoma mansoni | glutamate receptor kainate | 0.0099 | 0.1598 | 0.4874 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0099 | 0.1598 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0354 | 1 | 1 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0255 | 0.6722 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0099 | 0.1598 | 0.4874 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.015 | 0.3278 | 0.3278 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Echinococcus granulosus | glutamate receptor 2 | 0.015 | 0.3278 | 0.3278 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0099 | 0.1598 | 0.4874 |
Mycobacterium ulcerans | glutamine-binding lipoprotein GlnH | 0.0255 | 0.6722 | 0.5 |
Echinococcus multilocularis | NMDA receptor | 0.0099 | 0.1598 | 0.1598 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.015 | 0.3278 | 0.3278 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0099 | 0.1598 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0051 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor kainate | 0.0099 | 0.1598 | 0.4874 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0099 | 0.1598 | 0.4874 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.