Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0365 | 0.0297 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0362 | 0.4268 | 0.4228 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0362 | 0.4268 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0365 | 0.0855 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.007 | 0.0017 |
Echinococcus multilocularis | tumor protein p63 | 0.0396 | 0.4703 | 0.4666 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0362 | 0.4268 | 0.4238 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.007 | 0.0164 |
Brugia malayi | MAP kinase sur-1 | 0.0362 | 0.4268 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0362 | 0.4268 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.007 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Onchocerca volvulus | 0.0278 | 0.3184 | 1 | |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0362 | 0.4268 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.007 | 0.0164 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0244 | 0.2751 | 0.6445 |
Trypanosoma brucei | protein kinase, putative | 0.0362 | 0.4268 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0362 | 0.4268 | 0.4228 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0362 | 0.4268 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0362 | 0.4268 | 0.4228 |
Onchocerca volvulus | 0.0058 | 0.0365 | 0.0947 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0244 | 0.2751 | 0.6445 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0362 | 0.4268 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0362 | 0.4268 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0396 | 0.4703 | 0.4675 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0362 | 0.4268 | 0.4238 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.007 | 0.0164 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0362 | 0.4268 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.