Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0208 | 0.0711 | 0.0711 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0184 | 0.0515 | 0.0515 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0184 | 0.0515 | 0.1217 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0578 | 0.3845 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0623 | 0.4227 | 1 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.024 | 0.0986 | 0.0986 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0184 | 0.0515 | 0.0515 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0229 | 0.0896 | 0.212 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0229 | 0.0896 | 0.0896 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0165 | 0.0348 | 0.0822 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0208 | 0.0711 | 0.1682 |
Loa Loa (eye worm) | hypothetical protein | 0.0513 | 0.3297 | 0.8574 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0184 | 0.0515 | 0.1217 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0184 | 0.0515 | 0.1217 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0204 | 0.0677 | 0.0677 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.024 | 0.0986 | 0.0986 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0184 | 0.0515 | 0.0515 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0184 | 0.0515 | 0.0515 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0165 | 0.0348 | 0.0822 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0184 | 0.0515 | 0.1338 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0184 | 0.0515 | 0.1338 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0578 | 0.3845 | 0.3845 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0184 | 0.0515 | 0.1338 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.024 | 0.0986 | 0.2564 |
Echinococcus granulosus | voltage gated potassium channel | 0.0229 | 0.0896 | 0.0896 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.024 | 0.0986 | 0.2332 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0623 | 0.4227 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0578 | 0.3845 | 0.3845 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0208 | 0.0711 | 0.1849 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0208 | 0.0711 | 0.0711 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0208 | 0.0711 | 0.0711 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0184 | 0.0515 | 0.1217 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0184 | 0.0515 | 0.0515 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0184 | 0.0515 | 0.0515 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0184 | 0.0515 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.0515 | 0.1338 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0458 | 0.2831 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0184 | 0.0515 | 0.0515 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0229 | 0.0896 | 0.0896 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0184 | 0.0515 | 0.0515 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0184 | 0.0515 | 0.0515 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0229 | 0.0896 | 0.212 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0229 | 0.0896 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.0896 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.0711 | 0.1849 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0184 | 0.0515 | 0.1217 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0578 | 0.3845 | 1 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0184 | 0.0515 | 0.0515 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0229 | 0.0896 | 0.0896 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0458 | 0.2831 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0184 | 0.0515 | 0.1217 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0208 | 0.0711 | 0.1682 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.