Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ctsf protein | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0274 | 0.1018 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | fibroinase | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0274 | 0.0274 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0027 | 0.086 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | cathepsin B | 0.0051 | 0.2688 | 0.2482 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0051 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0274 | 0.3182 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0027 | 0.086 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0051 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.002 | 0.0274 | 0.0274 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.086 | 1 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Onchocerca volvulus | Cathepsin F homolog | 0.0027 | 0.086 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0051 | 0.2688 | 1 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0051 | 0.2688 | 0.2688 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0027 | 0.086 | 0.0603 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0274 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.086 | 0.086 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0027 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0051 | 0.2688 | 0.2688 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | cysteine protease | 0.0027 | 0.086 | 0.0603 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.002 | 0.0274 | 0.0274 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Toxoplasma gondii | cathepsin B | 0.0051 | 0.2688 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.