Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
471 records found | Showing page 18 of 19 (records 426-450) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
| M. tuberculosis | Rv3519 | OG5_229497 | Unknown protein |
| M. tuberculosis | Rv3522 | No group | Possible lipid transfer protein or keto acyl-CoA thiolase Ltp4 |
| M. tuberculosis | Rv3538 | OG5_129142 | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. |
| M. tuberculosis | Rv3548c | OG5_239168 | Probable short-chain type dehydrogenase/reductase |
| M. tuberculosis | Rv3556c | OG5_147360 | Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) |
| M. tuberculosis | Rv3559c | OG5_168406 | Probable oxidoreductase |
| M. tuberculosis | Rv3567c | OG5_133746 | Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9 ... |
| M. tuberculosis | Rv3572 | No group | Unknown protein |
| M. tuberculosis | Rv3610c | OG5_126616 | Membrane-bound protease FtsH (cell division protein) |
| M. tuberculosis | Rv3612c | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv3613c | No group | Hypothetical protein |
| M. tuberculosis | Rv3615c | OG5_237582 | ESX-1 secretion-associated protein EspC |
| M. tuberculosis | Rv3616c | OG5_237581 | ESX-1 secretion-associated protein A, EspA |
| M. tuberculosis | Rv3617 | OG5_129061 | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) |
| M. tuberculosis | Rv3618 | OG5_169842 | Possible monooxygenase |
| M. tuberculosis | Rv3639c | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv3640c | OG5_158048 | Probable transposase |
| M. tuberculosis | Rv3683 | OG5_131163 | Conserved protein |
| M. tuberculosis | Rv3704c | OG5_139531 | Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) ... |
| M. tuberculosis | Rv3706c | OG5_239173 | Conserved hypothetical proline rich protein |
| M. tuberculosis | Rv3734c | OG5_133846 | Putative triacylglycerol synthase (diacylglycerol acyltransferase) Tgs2 |
| M. tuberculosis | Rv3736 | OG5_156161 | Transcriptional regulatory protein (probably AraC/XylS-family) |
| M. tuberculosis | Rv3741c | No group | Possible oxidoreductase |
| M. tuberculosis | Rv3746c | OG5_239180 | Probable PE family protein PE34 (PE family-related protein) |