Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
993 records found | Showing page 3 of 40 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0154c | OG5_129853 | Probable acyl-CoA dehydrogenase FadE2 |
| M. tuberculosis | Rv0155 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic pa ... |
| M. tuberculosis | Rv0156 | OG5_141559 | Probable NAD(P) transhydrogenase (subunit alpha) PntAb [second part; integral me ... |
| M. tuberculosis | Rv0157 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] ... |
| M. tuberculosis | Rv0163 | OG5_139350 | Conserved protein |
| M. tuberculosis | Rv0164 | OG5_237838 | Conserved protein TB18.5 |
| M. tuberculosis | Rv0182c | OG5_179275 | Probable alternative RNA polymerase sigma factor SigG (RNA polymerase ECF type s ... |
| M. tuberculosis | Rv0183 | OG5_127037 | Possible lysophospholipase |
| M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
| M. tuberculosis | Rv0194 | OG5_126596 | Probable transmembrane multidrug efflux pump |
| M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase |
| M. tuberculosis | Rv0208c | OG5_127179 | Hypothetical methlytransferase (methylase) |
| M. tuberculosis | Rv0211 | OG5_129007 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoeno ... |
| M. tuberculosis | Rv0213c | OG5_133749 | Possible methyltransferase (methylase) |
| M. tuberculosis | Rv0220 | OG5_130169 | Probable esterase LipC |
| M. tuberculosis | Rv0222 | OG5_169926 | Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0223c | OG5_137356 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0228 | OG5_176236 | Probable integral membrane acyltransferase |
| M. tuberculosis | Rv0231 | OG5_209064 | Probable acyl-CoA dehydrogenase FadE4 |
| M. tuberculosis | Rv0233 | OG5_126823 | Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase ... |
| M. tuberculosis | Rv0234c | OG5_127004 | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 |
| M. tuberculosis | Rv0237 | OG5_130549 | Probable conserved lipoprotein LpqI |
| M. tuberculosis | Rv0247c | No group | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0248c | OG5_126927 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0249c | No group | Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogena ... |