Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 20 of 32 (records 476-500) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0194 | OG5_126596 | Probable transmembrane multidrug efflux pump |
| M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase |
| M. tuberculosis | Rv0208c | OG5_127179 | Hypothetical methlytransferase (methylase) |
| M. tuberculosis | Rv0247c | No group | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0248c | OG5_126927 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0259c | OG5_133515 | Conserved hypothetical protein |
| M. tuberculosis | Rv0260c | No group | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0282 | OG5_132590 | ESX conserved component EccA3. ESX-3 type VII secretion system protein. |
| M. tuberculosis | Rv0293c | OG5_239110 | Conserved protein |
| M. tuberculosis | Rv0303 | OG5_135402 | Probable dehydrogenase/reductase |
| M. tuberculosis | Rv0306 | OG5_146497 | Putative oxidoreductase |
| M. tuberculosis | Rv0315 | OG5_130926 | Possible beta-1,3-glucanase precursor |
| M. tuberculosis | Rv0316 | No group | Possible muconolactone isomerase |
| M. tuberculosis | Rv0329c | OG5_149664 | Conserved hypothetical protein |
| M. tuberculosis | Rv0331 | OG5_129122 | Possible dehydrogenase/reductase |
| M. tuberculosis | Rv0373c | OG5_127252 | Probable carbon monoxyde dehydrogenase (large chain) |
| M. tuberculosis | Rv0374c | OG5_134409 | Probable carbon monoxyde dehydrogenase (small chain) |
| M. tuberculosis | Rv0386 | OG5_160474 | Probable transcriptional regulatory protein (probably LuxR/UhpA-family) |
| M. tuberculosis | Rv0393 | OG5_166864 | Conserved 13E12 repeat family protein |
| M. tuberculosis | Rv0406c | OG5_138499 | Beta lactamase like protein |
| M. tuberculosis | Rv0421c | OG5_137082 | Conserved hypothetical protein |
| M. tuberculosis | Rv0434 | OG5_137743 | Conserved hypothetical protein |
| M. tuberculosis | Rv0439c | OG5_126621 | Probable dehydrogenase/reductase |
| M. tuberculosis | Rv0457c | OG5_156367 | Probable peptidase |
| M. tuberculosis | Rv0458 | OG5_126638 | Probable aldehyde dehydrogenase |