Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 19 of 32 (records 451-475) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3266c | OG5_128895 | dTDP-6-deoxy-L-lyxo-4-hexulose reductase RmlD (dTDP-rhamnose modification protei ... |
| M. tuberculosis | Rv2925c | OG5_127728 | Probable ribonuclease III Rnc (RNase III) |
| M. tuberculosis | Rv2902c | OG5_126908 | Probable ribonuclease HII protein RnhB (RNase HII) |
| M. tuberculosis | Rv2322c | OG5_215717 | Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid ... |
| M. tuberculosis | Rv1009 | OG5_171158 | Probable resuscitation-promoting factor RpfB |
| M. tuberculosis | Rv2389c | No group | Probable resuscitation-promoting factor RpfD |
| M. tuberculosis | Rv3457c | OG5_130460 | Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha cha ... |
| M. tuberculosis | Rv3251c | OG5_132030 | Probable rubredoxin RubA |
| M. tuberculosis | Rv2593c | OG5_132770 | Probable holliday junction DNA helicase RuvA |
| M. tuberculosis | Rv2592c | OG5_132500 | Probable holliday junction DNA helicase RuvB |
| M. tuberculosis | Rv0044c | OG5_146706 | Possible oxidoreductase |
| M. tuberculosis | Rv0068 | OG5_126621 | Probable oxidoreductase |
| M. tuberculosis | Rv0072 | OG5_153514 | Probable glutamine-transport transmembrane protein ABC transporter |
| M. tuberculosis | Rv0074 | OG5_133329 | Conserved protein |
| M. tuberculosis | Rv0075 | OG5_135774 | Probable aminotransferase |
| M. tuberculosis | Rv0077c | No group | Probable oxidoreductase |
| M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase |
| M. tuberculosis | Rv0083 | OG5_139265 | Probable oxidoreductase |
| M. tuberculosis | Rv0097 | OG5_129515 | Possible oxidoreductase |
| M. tuberculosis | Rv0130 | OG5_142681 | Probable 3-hydroxyl-thioester dehydratase |
| M. tuberculosis | Rv0133 | OG5_141414 | GCN5-related N-acetyltransferase |
| M. tuberculosis | Rv0139 | OG5_136762 | Possible oxidoreductase |
| M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
| M. tuberculosis | Rv0149 | OG5_130824 | Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) |
| M. tuberculosis | Rv0183 | OG5_127037 | Possible lysophospholipase |