Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
216 records found | Showing page 2 of 9 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv3704c | OG5_139531 | Glutamate--cysteine ligase GshA (gamma-glutamylcysteine synthetase) (gamma-ECS) ... |
M. tuberculosis | Rv0511 | OG5_128100 | Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methyla ... |
M. tuberculosis | Rv1601 | OG5_129258 | Probable imidazole glycerol-phosphate dehydratase HisB |
M. tuberculosis | Rv2121c | OG5_129102 | ATP phosphoribosyltransferase HisG |
M. tuberculosis | Rv1606 | OG5_131046 | Probable phosphoribosyl-AMP 1,6 cyclohydrolase HisI |
M. tuberculosis | Rv2711 | OG5_132027 | Iron-dependent repressor and activator IdeR |
M. tuberculosis | Rv3001c | OG5_129100 | Probable KETOL-acid reductoisomerase IlvC (acetohydroxy-acid isomeroreductase) ( ... |
M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
M. tuberculosis | Rv3002c | OG5_129345 | Probable acetolactate synthase (small subunit) IlvN (acetohydroxy-acid synthase) ... |
M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
M. tuberculosis | Rv3244c | OG5_237611 | Probable conserved lipoprotein LpqB |
M. tuberculosis | Rv1166 | OG5_237698 | Probable conserved lipoprotein LpqW |
M. tuberculosis | Rv3597c | OG5_237569 | Iron-regulated H-NS-like protein Lsr2 |
M. tuberculosis | Rv2378c | No group | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase) |
M. tuberculosis | Rv3625c | OG5_131037 | Possible cell cycle protein MesJ |
M. tuberculosis | Rv3341 | OG5_131823 | Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (hom ... |
M. tuberculosis | Rv1170 | OG5_174832 | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase Ms ... |
M. tuberculosis | Rv2157c | OG5_132578 | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-al ... |
M. tuberculosis | Rv0291 | OG5_149677 | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like prot ... |
M. tuberculosis | Rv1594 | OG5_132446 | Probable quinolinate synthetase NadA |
M. tuberculosis | Rv2421c | OG5_131883 | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophos ... |
M. tuberculosis | Rv2391 | OG5_132911 | Ferredoxin-dependent sulfite reductase SirA |
M. tuberculosis | Rv2841c | OG5_131885 | Probable N utilization substance protein A NusA |
M. tuberculosis | Rv1446c | OG5_181915 | Putative OXPP cycle protein OpcA |
M. tuberculosis | Rv3490 | OG5_129327 | Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosph ... |