Target list

Search results for query: Reweightable Leish rankings (12 criteria)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #339 (Leish no transmembrane domains): 20
  • Score for genes in query #337 (Leish enzymes): 100
  • Score for genes in query #345 (Leish genetic validation): 50
  • Score for genes in query #338 (Leish < 100 kDa): 20
  • Score for genes in query #343 (Leish not in humans): 25
  • Score for genes in query #347 (Leish compound desirability > 0.3): 35
  • Score for genes in query #340 (Leish PDB structure): 50
  • Score for genes in query #348 (Leish PubMed publications): 35
  • Score for genes in query #342 (Leish present in all TriTryps): 25
  • Score for genes in query #341 (Leish structural model (ModBase)): 30
  • Score for genes in query #344 (Leish essential): 40
  • Score for genes in query #346 (Leish druggability > 0.6): 35

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8205 records found | Showing page 328 of 329 (records 8176-8200) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.08.0850   OG5_130987   amastin-like protein 20
L. major   LmjF.04.0870   OG5_183150   hypothetical protein 20
L. major   LmjF.19.1050   OG5_183471   hypothetical protein, unknown function 20
L. major   LmjF.25.0100   OG5_166730   hypothetical protein, conserved 20
L. major   LmjF.34.0660   OG5_183494   hypothetical protein, unknown function 20
L. major   LmjF.08.0630   OG5_166008   hypothetical protein, unknown function 20
L. major   LmjF.20.0630   OG5_183546   hypothetical protein, conserved 20
L. major   LmjF.22.0640   OG5_183595   hypothetical protein, conserved 20
L. major   LmjF.31.2620   OG5_131648   hypothetical protein, conserved 20
L. major   LmjF.30.0850   OG5_157974   surface protein amastin, putative 20
L. major   LmjF.01.0010   OG5_183100   hypothetical protein, unknown function 20
L. major   LmjF.12.1210   OG5_183325   hypothetical protein, unknown function 20
L. major   LmjF.13.1310   OG5_183337   hypothetical protein, unknown function 20
L. major   LmjF.14.0370   OG5_182040   hypothetical protein, conserved 20
L. major   LmjF.15.1190   OG5_166695   hypothetical protein, conserved 20
L. major   LmjF.31.1310   OG5_166756   hypothetical protein, conserved 20
L. major   LmjF.32.1520   OG5_183966   hypothetical protein, conserved 20
L. major   LmjF.10.0660   OG5_183278   hypothetical protein, unknown function 20
L. major   LmjF.04.0790   OG5_183148   hypothetical protein, conserved 20
L. major   LmjF.32.1040   OG5_183958   hypothetical protein, conserved 20
L. major   LmjF.03.0820   OG5_183133   hypothetical protein, conserved 20
L. major   LmjF.33.2330   OG5_184047   hypothetical protein, unknown function 20
L. major   LmjF.32.0290   OG5_183950   hypothetical protein, conserved 20
L. major   LmjF.30.1170   OG5_175507   hypothetical protein, unknown function 20
L. major   LmjF.31.1330   OG5_183888   hypothetical protein, unknown function 20