Target list

Search results for query: Reweightable Leish rankings (12 criteria)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #343 (Leish not in humans): 25
  • Score for genes in query #340 (Leish PDB structure): 50
  • Score for genes in query #346 (Leish druggability > 0.6): 35
  • Score for genes in query #342 (Leish present in all TriTryps): 25
  • Score for genes in query #337 (Leish enzymes): 100
  • Score for genes in query #339 (Leish no transmembrane domains): 20
  • Score for genes in query #347 (Leish compound desirability > 0.3): 35
  • Score for genes in query #344 (Leish essential): 40
  • Score for genes in query #348 (Leish PubMed publications): 35
  • Score for genes in query #345 (Leish genetic validation): 50
  • Score for genes in query #341 (Leish structural model (ModBase)): 30
  • Score for genes in query #338 (Leish < 100 kDa): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8205 records found | Showing page 329 of 329 (records 8201-8205) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.25.0900   OG5_183672   hypothetical protein, unknown function 20
L. major   LmjF.31.2670   OG5_163884   hypothetical protein, unknown function 20
L. major   LmjF.36.5210   OG5_149113   hypothetical protein, conserved 20
L. major   LmjF.26.1260   OG5_183711   hypothetical protein, unknown function 20
L. major   LmjF.26.1460   OG5_183716   hypothetical protein, unknown function 20

Showing page 329 (records 8201-8205) of 329