Target list

Search results for query: Reweightable Leish rankings (12 criteria)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #342 (Leish present in all TriTryps): 25
  • Score for genes in query #339 (Leish no transmembrane domains): 20
  • Score for genes in query #337 (Leish enzymes): 100
  • Score for genes in query #338 (Leish < 100 kDa): 20
  • Score for genes in query #344 (Leish essential): 40
  • Score for genes in query #341 (Leish structural model (ModBase)): 30
  • Score for genes in query #347 (Leish compound desirability > 0.3): 35
  • Score for genes in query #343 (Leish not in humans): 25
  • Score for genes in query #340 (Leish PDB structure): 50
  • Score for genes in query #348 (Leish PubMed publications): 35
  • Score for genes in query #346 (Leish druggability > 0.6): 35
  • Score for genes in query #345 (Leish genetic validation): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8205 records found | Showing page 4 of 329 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
L. major   LmjF.06.1180   OG5_126822   protein kinase, putative 330
L. major   LmjF.36.0860   OG5_127304   mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 330
L. major   LmjF.36.2610   OG5_126889   folylpolyglutamate synthetase 330
L. major   LmjF.33.0365   OG5_126623   heat shock protein 83-1 330
L. major   LmjF.07.1030   OG5_128367   peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 330
L. major   LmjF.19.1530   OG5_126727   peptidylprolyl isomerase-like protein 330
L. major   LmjF.34.0330   OG5_144494   deoxyhypusine synthase;with=GeneDB:Linj34_V3.0350 330
L. major   LmjF.17.1390   OG5_126810   myo-inositol-1(or 4)-monophosphatase 1, putative 330
L. major   LmjF.28.0520   OG5_127024   protein kinase, putative 330
L. major   LmjF.24.2320   OG5_144825   mitogen-activated protein kinase 330
L. major   LmjF.36.3910   OG5_127233   S-adenosylhomocysteine hydrolase 330
L. major   LmjF.28.0890   OG5_126839   ribonucleoside-diphosphate reductase large chain, putative 330
L. major   LmjF.17.0790   OG5_127396   protein kinase, putative,polo-like protein kinase, putative 330
L. major   LmjF.32.0460   OG5_126583   prostaglandin f synthase, putative 330
L. major   LmjF.21.0840   OG5_127231   methionine aminopeptidase 2, putative 330
L. major   LmjF.29.2320   OG5_149772   mitogen activated protein kinase, putative 330
L. major   LmjF.33.0330   OG5_126623   heat shock protein 83-1 330
L. major   LmjF.31.2150   OG5_126583   prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 330
L. major   LmjF.18.1210   OG5_127154   prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putativ ... 330
L. major   LmjF.30.0800   OG5_128147   rac serine-threonine kinase, putative,protein kinase, putative 330
L. major   LmjF.30.3190   OG5_127955   3-hydroxy-3-methylglutaryl-CoA reductase 330
L. major   LmjF.34.0110   OG5_126762   adenylate kinase, putative 330
L. major   LmjF.13.1190   OG5_127011   adenylosuccinate synthetase, putative 330
L. major   LmjF.20.0250   OG5_127351   deoxyhypusine synthase, putative 330
L. major   LmjF.20.0110   OG5_126776   phosphoglycerate kinase B, cytosolic 330

Showing page 4 (records 76-100) of 329