Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
136 records found | Showing page 2 of 6 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0146 | OG5_135170 | Possible S-adenosylmethionine-dependent methyltransferase |
| M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
| M. tuberculosis | Rv0194 | OG5_126596 | Probable transmembrane multidrug efflux pump |
| M. tuberculosis | Rv0195 | No group | Possible two component transcriptional regulatory protein (probably LuxR-family) |
| M. tuberculosis | Rv0196 | OG5_191363 | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0213c | OG5_133749 | Possible methyltransferase (methylase) |
| M. tuberculosis | Rv0376c | OG5_138104 | Conserved hypothetical protein |
| M. tuberculosis | Rv0377 | OG5_171072 | Probable transcriptional regulatory protein (probably LysR-family) |
| M. tuberculosis | Rv0386 | OG5_160474 | Probable transcriptional regulatory protein (probably LuxR/UhpA-family) |
| M. tuberculosis | Rv0406c | OG5_138499 | Beta lactamase like protein |
| M. tuberculosis | Rv0517 | OG5_162561 | Possible membrane acyltransferase |
| M. tuberculosis | Rv0571c | OG5_168706 | Conserved protein |
| M. tuberculosis | Rv0572c | No group | Hypothetical protein |
| M. tuberculosis | Rv0576 | OG5_155587 | Probable transcriptional regulatory protein (possibly ArsR-family) |
| M. tuberculosis | Rv0650 | OG5_129253 | Possible sugar kinase |
| M. tuberculosis | Rv0669c | OG5_129670 | Possible hydrolase |
| M. tuberculosis | Rv0748 | OG5_204777 | Possible antitoxin VapB31 |
| M. tuberculosis | Rv0749 | OG5_166865 | Possible toxin VapC31. Contains PIN domain. |
| M. tuberculosis | Rv0794c | No group | Probable oxidoreductase |
| M. tuberculosis | Rv0795 | OG5_131793 | PUTATIVE TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS6110 (FRAGMENT) |
| M. tuberculosis | Rv0796 | OG5_128670 | Putative transposase for insertion sequence element IS6110 |
| M. tuberculosis | Rv0849 | OG5_149656 | Probable conserved integral membrane transport protein |
| M. tuberculosis | Rv1120c | OG5_126617 | Conserved hypothetical protein |
| M. tuberculosis | Rv1192 | No group | Unknown protein |
| M. tuberculosis | Rv1353c | OG5_178549 | Probable transcriptional regulatory protein |