Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
136 records found | Showing page 6 of 6 (records 126-136) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3186 | OG5_131793 | PROBABLE TRANSPOSASE FOR INSERTION SEQUENCE ELEMENT IS6110 (FRAGMENT) |
| M. tuberculosis | Rv3187 | OG5_128670 | Probable transposase |
| M. tuberculosis | Rv3188 | OG5_239149 | Conserved hypothetical protein |
| M. tuberculosis | Rv3448 | No group | ESX conserved component EccD4. ESX-4 type VII secretion system protein. Probable ... |
| M. tuberculosis | Rv3618 | OG5_169842 | Possible monooxygenase |
| M. tuberculosis | Rv3766 | No group | Hypothetical protein |
| M. tuberculosis | Rv3768 | OG5_234678 | Unknown protein |
| M. tuberculosis | Rv3889c | No group | ESX-2 secretion-associated protein EspG2 |
| M. tuberculosis | Rv1189 | OG5_164918 | Possible alternative RNA polymerase sigma factor SigI |
| M. tuberculosis | Rv3765c | OG5_128013 | Probable two component transcriptional regulatory protein TcrX |
| M. tuberculosis | Rv1759c | OG5_129879 | PE-PGRS family protein Wag22 |