Target list

Search results for query: Union of (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #7 (Growth Defect in C. elegans): 20
  • Score for genes in query #9 (Morphology Defect in C. elegans): 20
  • Score for genes in query #5 (any essentiality evidence): 5
  • Score for genes in query #3 (in mouse): -20
  • Score for genes in query #4 (in C. elegans): 10
  • Score for genes in query #2 (in human): -40
  • Score for genes in query #13 (bibliographic reference): 2
  • Score for genes in query #8 (Larval/Adult Lethal/Arrest in C. elegans): 40
  • Score for genes in query #10 (Sterility in C. elegans): 20
  • Score for genes in query #11 (3D model available): 2
  • Score for genes in query #12 (enzyme): 10
  • Score for genes in query #19 (druggable genes inferred by sequence simiarity): 30
  • Score for genes in query #6 (Embryonic Lethal/Arrest in C. elegans): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8930 records found | Showing page 3 of 358 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_38680   OG5_126605   tubulin alpha chain - mouse 117
B. malayi   Bm1_52575   OG5_179112   Protein kinase domain containing protein 117
B. malayi   Bm1_16230   OG5_192190   casein kinase II, putaitve 117
B. malayi   Bm1_14145   OG5_127382   protein phosphatase PP2A regulatory subunit 117
B. malayi   Bm1_44840   OG5_126817   Glutathione S-transferase, N-terminal domain containing protein 117
B. malayi   Bm1_44205   OG5_126705   V-type ATPase 116kDa subunit family protein 117
B. malayi   Bm1_12120   OG5_126605   alpha-tubulin 117
B. malayi   Bm1_55400   OG5_126605   Tubulin alpha-2 chain 117
B. malayi   Bm1_46210   OG5_128263   Protein kinase domain containing protein 117
B. malayi   Bm1_25035   OG5_126605   Tubulin alpha-2 chain 117
B. malayi   Bm1_48675   OG5_131088   GTP-binding regulatory protein Gs alpha-S chain, putative 117
B. malayi   Bm1_30260   OG5_126605   Tubulin alpha chain 117
B. malayi   Bm1_18685   OG5_189401   hypothetical protein 115
B. malayi   Bm1_54155   OG5_126745   Probable dimethyladenosine transferase 109
B. malayi   Bm1_20815   OG5_132787   integrin-linked kinase 109
B. malayi   Bm1_40910   OG5_126892   glutamate synthase 107
B. malayi   Bm1_40905   OG5_209097   Putative glutamate synthase 107
B. malayi   Bm1_17330   OG5_126927   succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 107
B. malayi   Bm1_41495   OG5_192637   Gex interacting protein protein 4 107
B. malayi   Bm1_50960   OG5_127237   vacuolar ATP synthase catalytic subunit A, osteoclast isoform 107
B. malayi   Bm1_53510   OG5_171353   myotactin form B 107
B. malayi   Bm1_48575   OG5_189673   BTB/POZ domain containing protein 107
B. malayi   Bm1_10280   OG5_126720   transketolase 107
B. malayi   Bm1_41830   OG5_126799   Alanyl-tRNA synthetase 107
B. malayi   Bm1_25665   OG5_146434   Ligand-binding domain of nuclear hormone receptor family protein 107

Showing page 3 (records 51-75) of 358