Target list

Search results for query: Union of (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19)

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  • Score for genes in query #5 (any essentiality evidence): 5
  • Score for genes in query #3 (in mouse): -20
  • Score for genes in query #8 (Larval/Adult Lethal/Arrest in C. elegans): 40
  • Score for genes in query #19 (druggable genes inferred by sequence simiarity): 30
  • Score for genes in query #7 (Growth Defect in C. elegans): 20
  • Score for genes in query #9 (Morphology Defect in C. elegans): 20
  • Score for genes in query #12 (enzyme): 10
  • Score for genes in query #11 (3D model available): 2
  • Score for genes in query #4 (in C. elegans): 10
  • Score for genes in query #10 (Sterility in C. elegans): 20
  • Score for genes in query #2 (in human): -40
  • Score for genes in query #6 (Embryonic Lethal/Arrest in C. elegans): 30
  • Score for genes in query #13 (bibliographic reference): 2

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8930 records found | Showing page 2 of 358 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_46790   OG5_128556   hypothetical protein 127
B. malayi   Bm1_22725   OG5_130286   RNA dependent RNA polymerase family protein 127
B. malayi   Bm1_44070   OG5_155013   Zinc finger, C2H2 type family protein 127
B. malayi   Bm1_12525   OG5_171279   RNA dependent RNA polymerase family protein 127
B. malayi   Bm1_16360   OG5_135009   ATPase, AAA family protein 127
B. malayi   Bm1_31340   OG5_126705   vacuolar proton pump 127
B. malayi   Bm1_55645   OG5_163210   mitochondria bc1 complex core subunit 1 127
B. malayi   Bm1_06555   OG5_192030   wnt family protein 125
B. malayi   Bm1_36575   OG5_192532   hypothetical protein 125
B. malayi   Bm1_35120   OG5_141166   PAN domain containing protein 125
B. malayi   Bm1_16340     No group hypothetical protein 125
B. malayi   Bm1_56530   OG5_186929   28S ribosomal protein S30, mitochondrial 125
B. malayi   Bm1_28045     No group hypothetical protein 125
B. malayi   Bm1_50890     No group Cuticle collagen 1 precursor 125
B. malayi   Bm1_52640   OG5_192877   hypothetical protein 125
B. malayi   Bm1_54115   OG5_192904   RH01479p 125
B. malayi   Bm1_41310   OG5_126677   Sars1 protein 119
B. malayi   Bm1_39760   OG5_126677   seryl-tRNA synthetase, mitochondrial precursor, putative 119
B. malayi   Bm1_35660   OG5_129488   Succinate dehydrogenase 117
B. malayi   Bm1_44630   OG5_126812   oxidoreductase, short chain dehydrogenase/reductase family protein 117
B. malayi   Bm1_20715   OG5_126605   tubulin alpha-2 chain 117
B. malayi   Bm1_28835   OG5_128511   Transcription initiation factor IIA, gamma subunit, helical domain containing pr ... 117
B. malayi   Bm1_32860   OG5_126723   Valyl-tRNA synthetase 117
B. malayi   Bm1_39900   OG5_131257   Sex muscle abnormal protein 5 117
B. malayi   Bm1_13170   OG5_174827   hypothetical protein 117

Showing page 2 (records 26-50) of 358