Target list

Search results for query: Union of (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #8 (any essentiality evidence): 3
  • Score for genes in query #7 (Sterility in C. elegans): 3
  • Score for genes in query #2 (Orthologs of D. melanogaster genes with mutant phenotype "neurophysiological defect"): 10
  • Score for genes in query #16 (Caffrey et al 's TOP 18): 0
  • Score for genes in query #13 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #3 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #10 (structural model available): 10
  • Score for genes in query #5 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #4 (Growth Defect in C. elegans): 3
  • Score for genes in query #1 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #17 (Caffrey et al 's TOP 35): 0
  • Score for genes in query #9 (in human): -20
  • Score for genes in query #14 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #6 (Morphology Defect in C. elegans): 3
  • Score for genes in query #15 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #12 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #11 (druggable genes inferred by sequence simiarity): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

10633 records found | Showing page 2 of 426 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_046600   OG5_126595   actin 68
S. mansoni   Smp_062300.1   OG5_126995   rac gtpase 68
S. mansoni   Smp_059790.2   OG5_126720   transketolase 68
S. mansoni   Smp_165490   OG5_127141   protein phsophatase-2a 68
S. mansoni   Smp_060420.3   OG5_127875   suppressor of actin (sac) 68
S. mansoni   Smp_027970   OG5_126599   ATP-dependent RNA Helicase 68
S. mansoni   Smp_028990.1   OG5_126821   protein phosphatase-1 68
S. mansoni   Smp_103790   OG5_126605   tubulin subunit alpha 68
S. mansoni   Smp_046590   OG5_126595   actin 68
S. mansoni   Smp_004810.3   OG5_126821   protein phosphatase type 1 65
S. mansoni   Smp_133990.1   OG5_128953   topbp1 65
S. mansoni   Smp_025800   OG5_127834   proteasome subunit beta 1 (T01 family) 65
S. mansoni   Smp_147050   OG5_127237   ATP synthase alpha subunit vacuolar 65
S. mansoni   Smp_079760.1   OG5_132787   protein kinase 65
S. mansoni   Smp_102040.3   OG5_127516   receptor for activated PKC 65
S. mansoni   Smp_102040.1   OG5_127516   receptor for activated PKC 65
S. mansoni   Smp_029390   OG5_127061   ATP synthase subunit beta vacuolar 65
S. mansoni   Smp_082490   OG5_126649   cyclin B 65
S. mansoni   Smp_130570   OG5_128637   receptor tyrosine phosphatase type r2a 65
S. mansoni   Smp_055770.1   OG5_182081   protein phosphatase 2a regulatory subunit 65
S. mansoni   Smp_134180   OG5_128637   receptor tyrosine phosphatase type r2a 65
S. mansoni   Smp_096310   OG5_131830   atypical protein kinase C 65
S. mansoni   Smp_144050   OG5_128637   receptor tyrosine phosphatase type r2a 65
S. mansoni   Smp_083720   OG5_127220   mitochondrial phosphate carrier protein 65
S. mansoni   Smp_121420   OG5_127597   N-myristoyltransferase 65

Showing page 2 (records 26-50) of 426