Target list

Search results for query: Union of (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #10 (structural model available): 10
  • Score for genes in query #13 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #3 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #16 (Caffrey et al 's TOP 18): 0
  • Score for genes in query #2 (Orthologs of D. melanogaster genes with mutant phenotype "neurophysiological defect"): 10
  • Score for genes in query #7 (Sterility in C. elegans): 3
  • Score for genes in query #8 (any essentiality evidence): 3
  • Score for genes in query #12 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #11 (druggable genes inferred by sequence simiarity): 20
  • Score for genes in query #15 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #6 (Morphology Defect in C. elegans): 3
  • Score for genes in query #14 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #9 (in human): -20
  • Score for genes in query #5 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #4 (Growth Defect in C. elegans): 3
  • Score for genes in query #1 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #17 (Caffrey et al 's TOP 35): 0

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

10633 records found | Showing page 426 of 426 (records 10626-10633) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_151800   OG5_141801   hypothetical protein -20
S. mansoni   Smp_066610.1   OG5_129950   hypothetical protein -20
S. mansoni   Smp_070760   OG5_128501   gas41 -20
S. mansoni   Smp_010450   OG5_137813   hypothetical protein -20
S. mansoni   Smp_113740   OG5_133169   hypothetical protein -20
S. mansoni   Smp_172120   OG5_133245   hypothetical protein -20
S. mansoni   Smp_104120   OG5_136189   hypothetical protein -20
S. mansoni   Smp_144260   OG5_135853   alpha-mannoside beta-16-n-acetylglucosaminyltransferase -20

Showing page 426 (records 10626-10633) of 426