Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 3 of 91 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| M. tuberculosis | Rv1185c | OG5_127582 | Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AM ... | 5 |
| M. tuberculosis | Rv0131c | OG5_239106 | Probable acyl-CoA dehydrogenase FadE1 | 5 |
| M. tuberculosis | Rv3274c | OG5_129653 | Probable acyl-CoA dehydrogenase FadE25 | 5 |
| M. tuberculosis | Rv2748c | OG5_130758 | Possible cell division transmembrane protein FtsK | 5 |
| M. tuberculosis | Rv2359 | OG5_130371 | Probable zinc uptake regulation protein Zur | 5 |
| M. tuberculosis | Rv2918c | OG5_138771 | Probable [protein-PII] uridylyltransferase GlnD (PII uridylyl- transferase) (uri ... | 5 |
| M. tuberculosis | Rv3859c | OG5_126892 | Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L ... | 5 |
| M. tuberculosis | Rv0511 | OG5_128100 | Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methyla ... | 5 |
| M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) | 5 |
| M. tuberculosis | Rv1600 | OG5_127656 | Probable histidinol-phosphate aminotransferase HisC1 | 5 |
| M. tuberculosis | Rv0085 | OG5_147565 | Possible hydrogenase HycP | 5 |
| M. tuberculosis | Rv3462c | OG5_130791 | Probable translation initiation factor if-1 InfA | 5 |
| M. tuberculosis | Rv1027c | OG5_136090 | Probable transcriptional regulatory protein KdpE | 5 |
| M. tuberculosis | Rv3290c | OG5_129508 | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysi ... | 5 |
| M. tuberculosis | Rv1399c | OG5_126961 | Probable non lipolytic carboxylesterase NlhH | 5 |
| M. tuberculosis | Rv1400c | OG5_126961 | Probable lipase LipH | 5 |
| M. tuberculosis | Rv2970c | OG5_126961 | Probable lipase/esterase LipN | 5 |
| M. tuberculosis | Rv0604 | OG5_193514 | Probable conserved lipoprotein LpqO | 5 |
| M. tuberculosis | Rv0671 | OG5_135121 | Possible conserved lipoprotein LpqP | 5 |
| M. tuberculosis | Rv3382c | OG5_130373 | Probable LYTB-related protein LytB1 | 5 |
| M. tuberculosis | Rv0170 | OG5_187193 | Mce-family protein Mce1B | 5 |
| M. tuberculosis | Rv3625c | OG5_131037 | Possible cell cycle protein MesJ | 5 |
| M. tuberculosis | Rv0676c | OG5_154987 | Probable conserved transmembrane transport protein MmpL5 | 5 |
| M. tuberculosis | Rv0869c | OG5_128145 | Probable molybdenum cofactor biosynthesis protein A2 MoaA2 | 5 |
| M. tuberculosis | Rv0864 | OG5_129779 | Probable molybdenum cofactor biosynthesis protein C 2 MoaC2 | 5 |