Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
143 records found | Showing page 6 of 6 (records 126-143) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| S. mansoni | Smp_002510 | OG5_127524 | pyruvate dehydrogenase (lipoamide) |
| S. mansoni | Smp_016670 | OG5_127905 | 4a-hydroxytetrahydrobiopterin dehydratase |
| S. mansoni | Smp_095540 | OG5_129173 | cytochrome-c oxidase |
| S. mansoni | Smp_177080 | OG5_128575 | alpha-1,3-mannosyltransferase |
| S. mansoni | Smp_181860 | OG5_246755 | folylpolyglutamate synthase |
| S. mansoni | Smp_070600 | OG5_127238 | transaldolase |
| S. mansoni | Smp_005390.2 | OG5_126899 | acetolactate synthase |
| S. mansoni | Smp_175230 | OG5_128410 | dihydrofolate reductase |
| S. mansoni | Smp_128690 | OG5_127334 | glycine dehydrogenase (decarboxylating) |
| S. mansoni | Smp_072090.3 | OG5_127857 | [ACP] S-malonyltransferase |
| S. mansoni | Smp_106150 | OG5_126835 | aspartate carbamoyltransferase |
| S. mansoni | Smp_009150.2 | OG5_126985 | 3-oxoacyl-[ACP] synthase |
| S. mansoni | Smp_109520 | OG5_127183 | 3-dehydroquinate synthase |
| S. mansoni | Smp_130860 | OG5_185011 | phenylalanine decarboxylase |
| S. mansoni | Smp_043350 | OG5_127359 | UDP-n-acetylglucosamine pyrophosphorylase |
| S. mansoni | Smp_013860 | OG5_128698 | glutamate-cysteine ligase |
| S. mansoni | Smp_050540 | OG5_126793 | orotidine 5'-phosphate decarboxylase |
| S. mansoni | Smp_150200 | OG5_129230 | not56-related |