Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
825 records found | Showing page 3 of 33 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| S. mansoni | Smp_143170 | OG5_127787 | mannosyl-oligosaccharidealpha-12-mannosidase-r el ated |
| S. mansoni | Smp_158420 | OG5_127800 | cathepsin B-like peptidase (C01 family) |
| S. mansoni | Smp_155560 | OG5_126693 | serine protease inhibitors serpins |
| S. mansoni | Smp_175560 | OG5_135830 | memapsin-2 (A01 family) |
| S. mansoni | Smp_001500 | OG5_127278 | eukaryotic translation initiation factor 4e |
| S. mansoni | Smp_084940.3 | OG5_133626 | GTP-binding protein rit |
| S. mansoni | Smp_029240.2 | OG5_127422 | protein arginine N-methyltransferase 1 |
| S. mansoni | Smp_013040.1 | OG5_126885 | cathepsin D (A01 family) |
| S. mansoni | Smp_123710 | OG5_127493 | acetyl-CoA carboxylase |
| S. mansoni | Smp_156220 | OG5_222433 | receptor tyrosine phosphatase type r2a |
| S. mansoni | Smp_142990 | OG5_126655 | serine/threonine protein kinase |
| S. mansoni | Smp_161470.1 | OG5_171802 | soluble guanylate cyclase gcy |
| S. mansoni | Smp_025160.3 | OG5_127329 | acyl-protein thioesterase 12 (lysophospholipase III) |
| S. mansoni | Smp_137170 | OG5_126645 | plasma membrane calcium-transporting atpase |
| S. mansoni | Smp_013540 | OG5_137498 | tyrosinase precursor |
| S. mansoni | Smp_194600 | OG5_128098 | mitochondrial carrier protein |
| S. mansoni | Smp_143430 | OG5_130088 | mannosidase alpha class 2a |
| S. mansoni | Smp_147250.1 | OG5_126561 | multidrug resistance protein |
| S. mansoni | Smp_141510 | OG5_172328 | family S9 non-peptidase homologue (S09 family) |
| S. mansoni | Smp_050390 | OG5_126638 | aldehyde dehydrogenase |
| S. mansoni | Smp_193800 | OG5_128364 | sodium/chloride dependent transporter |
| S. mansoni | Smp_104110 | OG5_126995 | gtpase_rho |
| S. mansoni | Smp_043670.2 | OG5_126758 | 6-phosphofructokinase |
| S. mansoni | Smp_162800.2 | OG5_130258 | protein kinase |
| S. mansoni | Smp_070860 | OG5_136609 | malate dehydrogenase |