Target list

Search results for query: Weighted ranking of Tbr targets involved in glycolysis for PLOS-NTD-version2

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #296 (Tbr modbase structures): 10
  • Score for genes in query #298 (Tbr Compound desirability > 0.2): 10
  • Score for genes in query #295 (Tbr PDB structure): 20
  • Score for genes in query #297 (Tbr Dindex >=0.4): 20
  • Score for genes in query #293 (Tbr all proteins): 1
  • Score for genes in query #299 (Tbr assayable): 20
  • Score for genes in query #294 (Tbr in Pubmed): 20
  • Score for genes in query #301 (uploaded weighted list of enzymes influencing glycolytic flux in Tbr): 0
  • Score for genes in query #300 (Tbr Glycolysis from KEGG): 1000

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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8299 records found | Showing page 332 of 332 (records 8276-8299) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. brucei   Tb927.2.4160   OG5_157948   hypothetical protein, conserved 1
T. brucei   Tb927.2.4445   OG5_148789   hypothetical protein, conserved 1
T. brucei   Tb927.2.4460   OG5_146047   Kinetoplast ribosomal PPR-repeat containing protein 21 1
T. brucei   Tb927.2.450   OG5_126555   retrotransposon hot spot protein 4 (RHS4), putative 1
T. brucei   Tb927.2.4700   OG5_151721   succinate dehydrogenase subunit 1
T. brucei   Tb927.2.4740   OG5_127103   mitochondrial ribosomal protein l11 1
T. brucei   Tb927.2.4920   OG5_128854   hypothetical protein, conserved 1
T. brucei   Tb927.2.4990   OG5_158029   hypothetical protein, conserved 1
T. brucei   Tb927.2.5070   OG5_148797   hypothetical protein, conserved 1
T. brucei   Tb927.2.510   OG5_126555   retrotransposon hot spot protein 4 (RHS4), putative 1
T. brucei   Tb927.2.5130   OG5_148798   hypothetical protein, conserved 1
T. brucei   Tb927.2.5140   OG5_154596   hypothetical protein, conserved 1
T. brucei   Tb927.2.5260   OG5_151908   hypothetical protein, conserved 1
T. brucei   Tb927.2.5530   OG5_137020   Present in the outer mitochondrial membrane proteome 22-1 1
T. brucei   Tb927.2.5630   OG5_236324   hypothetical protein, conserved 1
T. brucei   Tb927.2.5720     No group hypothetical protein 1
T. brucei   Tb927.2.5820   OG5_161948   hypothetical protein, conserved 1
T. brucei   Tb927.2.5900   OG5_146070   hypothetical protein, conserved 1
T. brucei   Tb927.2.6050   OG5_127760   beta prime COP protein 1
T. brucei   Tb927.2.650   OG5_152010   hypothetical protein 1
T. brucei   Tb927.2.680   OG5_142276   Protein of unknown function (DUF1181), putative 1
T. brucei   Tb927.2.900   OG5_152010   hypothetical protein 1
T. brucei   Tb927.2.940   OG5_142276   Protein of unknown function (DUF1181), putative 1
T. brucei   Tb927.2.960   OG5_185271   hypothetical protein 1

Showing page 332 (records 8276-8299) of 332