Target list

Search results for query: Union of (1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 12)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #6 (tcruzi genes essential in bacteria): 50
  • Score for genes in query #3 (tcruzi genes absent in human/mouse): 50
  • Score for genes in query #2 (tcruzi genes with 3D models): 30
  • Score for genes in query #11 (trypomastigote expression >= 1 spectrum): 2
  • Score for genes in query #5 (tcruzi genes essential in yeast): 50
  • Score for genes in query #1 (tcruzi genes with 3D structures): 40
  • Score for genes in query #4 (tcruzi genes with orthologs in T. brucei): 40
  • Score for genes in query #7 (tcruzi genes with moderately good druggability prediction): 60
  • Score for genes in query #10 (amastigote expression >= 2 spectra / 2 peptides): 6
  • Score for genes in query #12 (trypomastigote expression >=2 spectra >=2 peptides): 4
  • Score for genes in query #9 (amastigote expression >= 1 spectrum): 3

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18001 records found | Showing page 721 of 721 (records 18001-18001) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.504431.118   OG5_154613   hypothetical protein, conserved 2

Showing page 721 (records 18001-18001) of 721