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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
18001 records found | Showing page 1 of 721 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
T. cruzi | TcCLB.509153.90 | OG5_127385 | dihydrofolate reductase-thymidylate synthase | 270 |
T. cruzi | TcCLB.505763.19 | OG5_127253 | P-type H+-ATPase, putative | 245 |
T. cruzi | TcCLB.506621.30 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative | 235 |
T. cruzi | TcCLB.509203.70 | OG5_127113 | DNA topoisomerase II, putative | 230 |
T. cruzi | TcCLB.506529.340 | OG5_216555 | STE/STE11 serine/threonine-protein kinase, putative | 230 |
T. cruzi | TcCLB.509167.190 | OG5_164248 | STE/STE11 serine/threonine-protein kinase, putative | 230 |
T. cruzi | TcCLB.509167.100 | OG5_126723 | valyl-tRNA synthetase, putative | 230 |
T. cruzi | TcCLB.508699.10 | OG5_127113 | DNA topoisomerase II, putative | 230 |
T. cruzi | TcCLB.506649.20 | OG5_127253 | P-type H+-ATPase, putative | 230 |
T. cruzi | TcCLB.507019.10 | OG5_140087 | STE/STE11 serine/threonine-protein kinase, putative | 230 |
T. cruzi | TcCLB.506445.60 | OG5_128755 | mitochondrial DNA topoisomerase II, putative | 230 |
T. cruzi | TcCLB.508277.370 | OG5_128755 | mitochondrial DNA topoisomerase II, putative | 230 |
T. cruzi | TcCLB.510889.30 | OG5_216555 | STE/STE11 serine/threonine-protein kinase, putative | 230 |
T. cruzi | TcCLB.509065.180 | OG5_164248 | protein kinase-like protein, putative | 230 |
T. cruzi | TcCLB.508323.9 | OG5_127590 | farnesyl pyrophosphate synthase, putative | 220 |
T. cruzi | TcCLB.508647.200 | OG5_127002 | triosephosphate isomerase, putative | 212 |
T. cruzi | TcCLB.511555.80 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative | 200 |
T. cruzi | TcCLB.511287.49 | OG5_126583 | aldo-keto reductase | 195 |
T. cruzi | TcCLB.508909.20 | OG5_126887 | GMP reductase | 195 |
T. cruzi | TcCLB.509233.180 | OG5_127099 | ATP synthase subunit beta, mitochondrial, putative | 195 |
T. cruzi | TcCLB.506519.130 | OG5_126887 | GMP reductase | 195 |
T. cruzi | TcCLB.511823.70 | OG5_127590 | farnesyl pyrophosphate synthase | 190 |
T. cruzi | TcCLB.510149.80 | OG5_126568 | ABC transporter, putative | 189 |
T. cruzi | TcCLB.506989.30 | OG5_126568 | ABC transporter, putative | 189 |
T. cruzi | TcCLB.510943.50 | OG5_128522 | delta-1-pyrroline-5-carboxylate dehydrogenase, putative | 186 |