Target list

Search results for query: PLoS NTD Query 11 (S. mansoni)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #273 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #262 (structural model available): 10
  • Score for genes in query #254 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #271 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #266 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #256 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #260 (Sterility in C. elegans): 3
  • Score for genes in query #259 (Morphology Defect in C. elegans): 3
  • Score for genes in query #255 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #265 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #270 (Sma in Cel): 10
  • Score for genes in query #267 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #261 (any essentiality evidence): 3
  • Score for genes in query #272 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #258 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #264 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #263 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #268 (Sma all proteins): 1
  • Score for genes in query #253 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #257 (Growth Defect in C. elegans): 3

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12561 records found | Showing page 4 of 503 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_079770.3   OG5_126843   Probable protein disulfide-isomerase ER-60 precursor (ERP60) 92
S. mansoni   Smp_040970.3   OG5_126705   vacuolar proton atpases 92
S. mansoni   Smp_028730   OG5_127109   glucosamine-1-phosphate N-acetyltransferase 92
S. mansoni   Smp_030710   OG5_127639   protein phsophatase-2a 90
S. mansoni   Smp_151100   OG5_175260   serine/threonine protein kinase 90
S. mansoni   Smp_194610   OG5_126748   serine/threonine protein kinase 90
S. mansoni   Smp_026510   OG5_127304   protein kinase 90
S. mansoni   Smp_092750   OG5_126708   nucleoside diphosphate kinase 90
S. mansoni   Smp_179950   OG5_127800   cathepsin B-like peptidase (C01 family) 90
S. mansoni   Smp_121430.2   OG5_127761   proteasome subunit beta 3 (T01 family) 89
S. mansoni   Smp_046060.1   OG5_126577   myosin heavy chain type B 89
S. mansoni   Smp_171540.1   OG5_162739   Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp) 89
S. mansoni   Smp_128610   OG5_133034   cytochrome-c oxidase 89
S. mansoni   Smp_161920   OG5_126595   actin 89
S. mansoni   Smp_099930   OG5_129860   f-box and wd40 domain protein 89
S. mansoni   Smp_085540.4   OG5_126577   myosin heavy chain 89
S. mansoni   Smp_034840.2   OG5_126706   hypothetical protein 89
S. mansoni   Smp_089590   OG5_127555   mannose-6-phosphate isomerase 89
S. mansoni   Smp_035470   OG5_128922   dolichyl-diphosphooligosaccharide-protein glycosyltransferase 89
S. mansoni   Smp_079220   OG5_126841   ADPATP carrier protein 89
S. mansoni   Smp_041600   OG5_126684   isoleucine--tRNA ligase 89
S. mansoni   Smp_053510.1   OG5_127227   aspartyl-tRNA synthetase 89
S. mansoni   Smp_053610   OG5_126677   seryl-tRNA synthetase 89
S. mansoni   Smp_038240   OG5_126799   alanyl-tRNA synthetase 89
S. mansoni   Smp_009760   OG5_142874   hypothetical protein 89

Showing page 4 (records 76-100) of 503