Target list

Search results for query: PLoS NTD Query 11 (S. mansoni)

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  • Score for genes in query #265 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #260 (Sterility in C. elegans): 3
  • Score for genes in query #268 (Sma all proteins): 1
  • Score for genes in query #258 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #271 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #255 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #262 (structural model available): 10
  • Score for genes in query #266 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #256 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #261 (any essentiality evidence): 3
  • Score for genes in query #259 (Morphology Defect in C. elegans): 3
  • Score for genes in query #273 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #253 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #267 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #254 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #272 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #264 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #257 (Growth Defect in C. elegans): 3
  • Score for genes in query #270 (Sma in Cel): 10
  • Score for genes in query #263 (druggable genes inferred by sequence simiarity): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12561 records found | Showing page 3 of 503 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_073410   OG5_127705   proteasome catalytic subunit 2 (T01 family) 96
S. mansoni   Smp_079760.2   OG5_132787   protein kinase 96
S. mansoni   Smp_004810.1   OG5_126821   protein phosphatase type 1 96
S. mansoni   Smp_007260.2   OG5_126674   ATPase 96
S. mansoni   Smp_144030   OG5_127441   phosphatidate cytidylyltransferase 93
S. mansoni   Smp_152330   OG5_126748   serine/threonine protein kinase 93
S. mansoni   Smp_173810   OG5_126981   protein phosphatase pp2a regulatory subunit B 93
S. mansoni   Smp_008260   OG5_126888   glycogen synthase kinase 3-related (gsk3) (cmgc group III) 93
S. mansoni   Smp_194270   OG5_246867   kinase 93
S. mansoni   Smp_044920   OG5_126660   dynamin 93
S. mansoni   Smp_055890   OG5_126823   ribonucleoside-diphosphate reductase small chain 93
S. mansoni   Smp_040570.1   OG5_126724   rab5 93
S. mansoni   Smp_005210   OG5_126742   histone deacetylase 93
S. mansoni   Smp_024110   OG5_126698   phosphopyruvate hydratase 93
S. mansoni   Smp_141610   OG5_127800   SmCB2 peptidase (C01 family) 93
S. mansoni   Smp_046740   OG5_126968   dihydrolipoamide dehydrogenase 93
S. mansoni   Smp_169950   OG5_126780   serine/threonine protein kinase 93
S. mansoni   Smp_040570.2   OG5_126724   rab5 93
S. mansoni   Smp_067810   OG5_126780   protein kinase 93
S. mansoni   Smp_012930   OG5_126887   inosine-5-monophosphate dehydrogenase 93
S. mansoni   Smp_130300   OG5_127003   na+/k+ atpase alpha subunit 93
S. mansoni   Smp_079770.1   OG5_126843   protein disulfide-isomerase er-60 precursor (erp60) 92
S. mansoni   Smp_060950   OG5_127387   soluble NSF attachment protein (SNAP) 92
S. mansoni   Smp_059340.3   OG5_131088   Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimula ... 92
S. mansoni   Smp_056760   OG5_126843   protein disulfide-isomerase 92

Showing page 3 (records 51-75) of 503