Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2240 records found | Showing page 3 of 90 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase | 328 |
M. tuberculosis | Rv2631 | OG5_127467 | Conserved hypothetical protein | 328 |
M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... | 327 |
M. tuberculosis | Rv1404 | OG5_160441 | Probable transcriptional regulatory protein | 327 |
M. tuberculosis | Rv2878c | OG5_129566 | Soluble secreted antigen Mpt53 precursor | 326 |
M. tuberculosis | Rv2036 | OG5_239152 | Conserved hypothetical protein | 326 |
M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... | 322 |
M. tuberculosis | Rv0559c | OG5_237782 | Possible conserved secreted protein | 320 |
M. tuberculosis | Rv1405c | OG5_176030 | Putative methyltransferase | 320 |
M. tuberculosis | Rv3801c | OG5_127582 | Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthas ... | 319 |
M. tuberculosis | Rv1493 | OG5_130968 | Probable methylmalonyl-CoA mutase large subunit MutB (MCM) | 319 |
M. tuberculosis | Rv1806 | OG5_132981 | PE family protein PE20 | 319 |
M. tuberculosis | Rv2500c | OG5_128729 | Possible acyl-CoA dehydrogenase FadE19 (MMGC) | 318 |
M. tuberculosis | Rv0834c | OG5_129879 | PE-PGRS family protein PE_PGRS14 | 317 |
M. tuberculosis | Rv3437 | No group | Possible conserved transmembrane protein | 316 |
M. tuberculosis | Rv0827c | OG5_129305 | Metal sensor transcriptional regulator KmtR (ArsR-SmtB family) | 315 |
M. tuberculosis | Rv1894c | OG5_141344 | Conserved hypothetical protein | 315 |
M. tuberculosis | Rv3776 | OG5_166864 | Conserved hypothetical protein | 315 |
M. tuberculosis | Rv3572 | No group | Unknown protein | 310 |
M. tuberculosis | Rv0455c | OG5_237795 | Conserved protein | 305 |
M. tuberculosis | Rv3615c | OG5_237582 | ESX-1 secretion-associated protein EspC | 304 |
M. tuberculosis | Rv0752c | OG5_136059 | Probable acyl-CoA dehydrogenase FadE9 | 303 |
M. tuberculosis | Rv2466c | OG5_237696 | Conserved protein | 303 |
M. tuberculosis | Rv3406 | OG5_129515 | Probable dioxygenase | 302 |
M. tuberculosis | Rv3416 | OG5_237579 | Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster. | 299 |