Target list

Search results for query: Weighted list for comparison of PLOS-NTD's vs. this B. malayi targets prioritization

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  • Score for genes in query #27 (B. malayi orthologs of C. elegans genes differentially expressed in neurons): 30
  • Score for genes in query #39 (Bma in PDB): 5
  • Score for genes in query #45 ( top-100 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0
  • Score for genes in query #36 (Bma - morphology defect in Cel): 20
  • Score for genes in query #30 (Bma modbase): 2
  • Score for genes in query #35 (Bma - larval/adult lethal/arrest in Cel): 40
  • Score for genes in query #34 (Bma - growth defect in Cel): 20
  • Score for genes in query #23 (B. malayi orthologs of C. elegans genes differentially expressed in muscle): 30
  • Score for genes in query #33 (Bma - embryonic lethal/arrest in Cel): 30
  • Score for genes in query #38 (Bma any EC): 10
  • Score for genes in query #32 (Bma in Cel): 10
  • Score for genes in query #40 (Bma assayable): 5
  • Score for genes in query #28 (Bma druggable precedence by similarity to starlite targets): 30
  • Score for genes in query #37 (Bma any essentiality): 5
  • Score for genes in query #29 (Bma - sterile in Cel): 20
  • Score for genes in query #44 ( top-25 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0
  • Score for genes in query #41 (Bma all proteins): 1
  • Score for genes in query #31 (Bma pubmed): 2

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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11305 records found | Showing page 4 of 453 (records 76-100) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_04450   OG5_126577   Paramyosin 178
B. malayi   Bm1_30720   OG5_127549   KE2 family protein 178
B. malayi   Bm1_29875   OG5_126569   Histone H3.3 176
B. malayi   Bm1_23080   OG5_131071   ATP synthase f chain, mitochondrial 176
B. malayi   Bm1_31230   OG5_129041   Ribophorin I family protein 176
B. malayi   Bm1_10280   OG5_126720   transketolase 173
B. malayi   Bm1_54155   OG5_126745   Probable dimethyladenosine transferase 170
B. malayi   Bm1_20815   OG5_132787   integrin-linked kinase 170
B. malayi   Bm1_26800   OG5_128006   Cytochrome C1 family protein 170
B. malayi   Bm1_03920   OG5_133034   Cytochrome c oxidase subunit IV family protein 170
B. malayi   Bm1_50960   OG5_127237   vacuolar ATP synthase catalytic subunit A, osteoclast isoform 168
B. malayi   Bm1_41830   OG5_126799   Alanyl-tRNA synthetase 168
B. malayi   Bm1_51640   OG5_127762   Proteasome A-type and B-type family protein 168
B. malayi   Bm1_16555   OG5_129868   hypothetical protein 168
B. malayi   Bm1_32455   OG5_127555   mannose-6-phosphate isomerase, class I family protein 168
B. malayi   Bm1_34625   OG5_127362   Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehy ... 168
B. malayi   Bm1_32605   OG5_128099   RAS-like GTP-binding protein RhoA 168
B. malayi   Bm1_28480   OG5_126923   translation elongation factor aEF-2 168
B. malayi   Bm1_14125   OG5_127834   proteasome subunit beta type 1 168
B. malayi   Bm1_12165   OG5_127626   methionyl-tRNA synthetase 168
B. malayi   Bm1_24615   OG5_132535   ATP synthase B chain, mitochondrial precursor 168
B. malayi   Bm1_57260   OG5_127404   ATP synthase delta chain, mitochondrial precursor, putative 168
B. malayi   Bm1_52850   OG5_127555   mannose-6-phosphate isomerase, class I family protein 168
B. malayi   Bm1_27290   OG5_128099   RAS-like GTP-binding protein RhoA 168
B. malayi   Bm1_24805   OG5_127761   proteasome subunit beta type 3 168

Showing page 4 (records 76-100) of 453