Target list

Search results for query: Weighted list for comparison of PLOS-NTD's vs. this B. malayi targets prioritization

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  • Score for genes in query #36 (Bma - morphology defect in Cel): 20
  • Score for genes in query #45 ( top-100 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0
  • Score for genes in query #33 (Bma - embryonic lethal/arrest in Cel): 30
  • Score for genes in query #23 (B. malayi orthologs of C. elegans genes differentially expressed in muscle): 30
  • Score for genes in query #37 (Bma any essentiality): 5
  • Score for genes in query #29 (Bma - sterile in Cel): 20
  • Score for genes in query #31 (Bma pubmed): 2
  • Score for genes in query #34 (Bma - growth defect in Cel): 20
  • Score for genes in query #30 (Bma modbase): 2
  • Score for genes in query #27 (B. malayi orthologs of C. elegans genes differentially expressed in neurons): 30
  • Score for genes in query #32 (Bma in Cel): 10
  • Score for genes in query #41 (Bma all proteins): 1
  • Score for genes in query #39 (Bma in PDB): 5
  • Score for genes in query #40 (Bma assayable): 5
  • Score for genes in query #35 (Bma - larval/adult lethal/arrest in Cel): 40
  • Score for genes in query #38 (Bma any EC): 10
  • Score for genes in query #28 (Bma druggable precedence by similarity to starlite targets): 30
  • Score for genes in query #44 ( top-25 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data): 0

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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11305 records found | Showing page 3 of 453 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_57375   OG5_126993   60S ribosomal protein L9 178
B. malayi   Bm1_45995   OG5_126812   oxidoreductase, short chain dehydrogenase/reductase family protein 178
B. malayi   Bm1_39900   OG5_131257   Sex muscle abnormal protein 5 178
B. malayi   Bm1_18445   OG5_126577   heavy chain, unconventional myosin protein 2 178
B. malayi   Bm1_31690   OG5_132429   SPARC precursor 178
B. malayi   Bm1_41735   OG5_127497   60S ribosomal protein L24 178
B. malayi   Bm1_43675   OG5_126588   heat shock 70 kDa protein 178
B. malayi   Bm1_38460   OG5_128087   cytochrome oxidase c subunit VIb family protein 178
B. malayi   Bm1_20955   OG5_127033   60S ribosomal protein L15 178
B. malayi   Bm1_30930   OG5_127340   MyTH4 domain containing protein 178
B. malayi   Bm1_00935   OG5_126577   myosin heavy chain B (MHC B) 178
B. malayi   Bm1_53760   OG5_128087   cytochrome-c oxidase 178
B. malayi   Bm1_00655   OG5_126577   myosin heavy chain, nonmuscle type 1 178
B. malayi   Bm1_51435   OG5_126577   Myosin tail family protein 178
B. malayi   Bm1_25145   OG5_127839   NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial 178
B. malayi   Bm1_44205   OG5_126705   V-type ATPase 116kDa subunit family protein 178
B. malayi   Bm1_00275   OG5_127430   S-phase kinase-associated protein SKR-1 178
B. malayi   Bm1_38795   OG5_126696   ADP-ribosylation factor 4 178
B. malayi   Bm1_46210   OG5_128263   Protein kinase domain containing protein 178
B. malayi   Bm1_07645   OG5_126588   heat shock 70 kDa protein C precursor 178
B. malayi   Bm1_38090   OG5_127839   Probable NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrialprecursor 178
B. malayi   Bm1_48675   OG5_131088   GTP-binding regulatory protein Gs alpha-S chain, putative 178
B. malayi   Bm1_02495   OG5_126569   histone H3 178
B. malayi   Bm1_20770   OG5_128019   NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial precursor 178
B. malayi   Bm1_30225   OG5_127498   Dynein light chain 1, cytoplasmic 178

Showing page 3 (records 51-75) of 453