Target list

Search results for query: Union of (49, 50, 52, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 67, 68, 69, 70, 71, 72, 73, 81)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #63 (has Signal Peptide): -3
  • Score for genes in query #62 (has GPI anchor signal): -3
  • Score for genes in query #67 (ortholog essential in E. coli): 12
  • Score for genes in query #81 (nucleotide-diversity-normalized): var
  • Score for genes in query #58 (Pubmed): 12
  • Score for genes in query #64 (has EC number): 9
  • Score for genes in query #70 (ortholog in C. elegans has 'embryonic arrest' RNAi phenotype): 12
  • Score for genes in query #50 (tcr expression trypos-amas 1,5 fold 0.8 confidence): 12
  • Score for genes in query #61 (tcr > 2 paralogs): -18
  • Score for genes in query #68 (ortholog essential in M. tuberculosis): 12
  • Score for genes in query #55 (tcr doesn't have ortholog in mammals): 12
  • Score for genes in query #71 (is enzyme): 15
  • Score for genes in query #73 (has 3D structure(s)): 20
  • Score for genes in query #60 (has >= 1 TM domain): -3
  • Score for genes in query #56 (Assayability - Assay Available): 7
  • Score for genes in query #52 (tcr has ortholog in kinetoplastida): 9
  • Score for genes in query #72 (has 3D model(s)): 20
  • Score for genes in query #59 (tcr MW < 100 kDa): 9
  • Score for genes in query #57 (Assayability - Soluble): 7
  • Score for genes in query #69 (ortholog essential in S. cerevisiae): 12
  • Score for genes in query #49 ( tcr expression epis-amas 1,5 fold 0.8 confidence): 12

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18625 records found | Showing page 2 of 745 (records 26-50) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.510661.270   OG5_127045   replication factor C, subunit 3, putative 184
T. cruzi   TcCLB.506195.80   OG5_126762   adenylate kinase, putative 183
T. cruzi   TcCLB.507611.370   OG5_126843   bloodstream- specific protein 2 precursor 183
T. cruzi   TcCLB.509611.20   OG5_128367   peptidyl-prolyl cis-trans isomerase 183
T. cruzi   TcCLB.506629.70   OG5_126959   cysteine desulfurase, putative 181
T. cruzi   TcCLB.506297.190   OG5_127082   pyruvate phosphate dikinase, putative 181
T. cruzi   TcCLB.507775.50   OG5_127755   proteasome alpha 7 subunit, putative 181
T. cruzi   TcCLB.503935.20   OG5_127362   2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase ... 181
T. cruzi   TcCLB.506261.10   OG5_126601   fatty acyl CoA synthetase 2, putative 181
T. cruzi   TcCLB.510947.10   OG5_127109   GDP-mannose pyrophosphorylase 181
T. cruzi   TcCLB.504003.70   OG5_127913   S-adenosyl-methyltransferase mraW-like protein, putative 180
T. cruzi   TcCLB.508993.10   OG5_126851   cytidine triphosphate synthase, putative 180
T. cruzi   TcCLB.506701.10   OG5_149690   dihydrolipoamide dehydrogenase, putative 180
T. cruzi   TcCLB.511649.150   OG5_129378   phosphoglycerate mutase protein, putative 179
T. cruzi   TcCLB.511165.70   OG5_127424   proteasome alpha 7 subunit, putative 179
T. cruzi   TcCLB.505999.90   OG5_126776   phosphoglycerate kinase, putative 179
T. cruzi   TcCLB.506559.530   OG5_132454   protein phosphatase 2C, putative 179
T. cruzi   TcCLB.508153.510   OG5_150111   Serine/threonine-protein kinase NEK6, putative 178
T. cruzi   TcCLB.511653.20   OG5_141243   dual-specificity protein phosphatase, putative 178
T. cruzi   TcCLB.508851.189   OG5_152691   phosphoenolpyruvate mutase, putative 178
T. cruzi   TcCLB.507601.70   OG5_128117   dihydrolipoamide branched chain transacylase, putative 178
T. cruzi   TcCLB.508971.50   OG5_127551   ubiquitin-protein ligase-like, putative 177
T. cruzi   TcCLB.427789.30   OG5_127076   NAD+ synthase, putative 177
T. cruzi   TcCLB.508999.200   OG5_146880   cysteine peptidase, Clan CA, family C2, putative 177
T. cruzi   TcCLB.508933.20   OG5_138783   dihydrolipoamide dehydrogenase, putative 177

Showing page 2 (records 26-50) of 745