Target list

Search results for query: Union of (#1, #2, #7, #8)

  • Score for genes in query #2 (Plasmodium falciparum genes present in parasites and yeast but absent in animals): 20
  • Score for genes in query #8 (Plamodium falciparum genes with any essentiality ): 50
  • Score for genes in query #7 (Plasmodium falciparum genes with druggability index higher than 0.7): 40
  • Score for genes in query #1 (Plasmodium falciparum enzymes with structure): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

1481 records found | Showing page 60 of 60 (records 1476-1481) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1238800   OG5_150506   acyl-CoA synthetase 10
P. falciparum   PF3D7_1242200   OG5_126946   queuine tRNA-ribosyltransferase, putative 10
P. falciparum   PF3D7_1245300   OG5_128611   NEDD8-conjugating enzyme UBC12, putative 10
P. falciparum   PF3D7_1247800   OG5_130494   dipeptidyl aminopeptidase 2 10
P. falciparum   PF3D7_1252200   OG5_141486   chitinase 10
P. falciparum   PF3D7_1253400   OG5_136613   acyl-CoA synthetase 10

Showing page 60 (records 1476-1481) of 60