Target list

Search results for query: Union of (#1, #2, #7, #8)

  • Score for genes in query #7 (Plasmodium falciparum genes with druggability index higher than 0.7): 40
  • Score for genes in query #1 (Plasmodium falciparum enzymes with structure): 10
  • Score for genes in query #8 (Plamodium falciparum genes with any essentiality ): 50
  • Score for genes in query #2 (Plasmodium falciparum genes present in parasites and yeast but absent in animals): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

1481 records found | Showing page 59 of 60 (records 1451-1475) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0908600   OG5_127766   ribosomal RNA methyltransferase, putative 10
P. falciparum   PF3D7_0908700   OG5_126786   tRNA pseudouridine synthase, putative 10
P. falciparum   PF3D7_0914200   OG5_137233   phospholipid or glycerol acyltransferase, putative 10
P. falciparum   PF3D7_0915400   OG5_131114   ATP-dependent 6-phosphofructokinase 10
P. falciparum   PF3D7_0918000   OG5_129627   glideosome-associated protein 50 10
P. falciparum   PF3D7_0918900   OG5_128698   gamma-glutamylcysteine synthetase 10
P. falciparum   PF3D7_0919400   OG5_165925   protein disulfide isomerase 10
P. falciparum   PF3D7_0921000   OG5_127012   ubiquitin-conjugating enzyme E2, putative 10
P. falciparum   PF3D7_0927900   OG5_128421   phosphatidylserine decarboxylase 10
P. falciparum   PF3D7_0928000   OG5_128087   cytochrome c oxidase subunit 6B, putative 10
P. falciparum   PF3D7_0930500   OG5_155356   diacylglycerol kinase, putative 10
P. falciparum   PF3D7_0932300   OG5_128020   M18 aspartyl aminopeptidase 10
P. falciparum   PF3D7_1202400   OG5_147417   peptidyl-prolyl cis-trans isomerase 10
P. falciparum   PF3D7_1205700   OG5_162972   targeted glyoxalase II 10
P. falciparum   PF3D7_1206400   OG5_127129   rhodanese like protein, putative 10
P. falciparum   PF3D7_1209500   OG5_152655   cGMP-specific phosphodiesterase 10
P. falciparum   PF3D7_1214400   OG5_129667   ER membrane protein complex subunit 6, putative 10
P. falciparum   PF3D7_1215200   OG5_147406   peptidyl-prolyl cis-trans isomerase 10
P. falciparum   PF3D7_1219600   OG5_126610   aminophospholipid-transporting P-ATPase 10
P. falciparum   PF3D7_1226100   OG5_160534   haloacid dehalogenase-like hydrolase, putative 10
P. falciparum   PF3D7_1226600   OG5_140126   proliferating cell nuclear antigen 2 10
P. falciparum   PF3D7_1227900   OG5_137871   RNA pseudouridylate synthase, putative 10
P. falciparum   PF3D7_1231100   OG5_128031   ras-related protein Rab-2 10
P. falciparum   PF3D7_1232000   OG5_167491   phenylalanine--tRNA ligase 10
P. falciparum   PF3D7_1238600   OG5_155011   sphingomyelin phosphodiesterase 10