Target list

Search results for query: Mtb, essentail in Mtb only

  • Essential: mtu essential
  • Species: mtu
Show: all curated predicted compounds associated with these genes.

Compounds have been manually associated with targets based on literature curation (curated), and transitively associated with direct orthologs (predicted). Please note that a link between a compound and a target does not imply an outstanding activity (e.g. inhibition). In many cases the association serves the only purpose of showing that e.g. "compound X" has been tested against "target Y", even if there was no detectable activity in the assay. Information about each assay and its outcome is available for each compound.

460 records found | Showing page 1 of 19 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
M. tuberculosis   Rv0005   OG5_128755   DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ...
M. tuberculosis   Rv0014c   OG5_146588   Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B)
M. tuberculosis   Rv0015c   OG5_155711   Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)
M. tuberculosis   Rv0058   OG5_131890   Probable replicative DNA helicase DnaB
M. tuberculosis   Rv0060   OG5_133608   Conserved hypothetical protein
M. tuberculosis   Rv0085   OG5_147565   Possible hydrogenase HycP
M. tuberculosis   Rv0086   OG5_134238   Possible hydrogenase HycQ
M. tuberculosis   Rv0102   OG5_156768   Probable conserved integral membrane protein
M. tuberculosis   Rv0107c   OG5_215400   Probable cation-transporter ATPase I CtpI
M. tuberculosis   Rv0112   OG5_149659   Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase)
M. tuberculosis   Rv0118c   OG5_126899   Probable oxalyl-CoA decarboxylase OxcA
M. tuberculosis   Rv0119   OG5_126609   Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA ...
M. tuberculosis   Rv0127   OG5_239105   Maltokinase Mak
M. tuberculosis   Rv0148   OG5_129142   Probable short-chain type dehydrogenase/reductase
M. tuberculosis   Rv0166   OG5_126609   Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA ...
M. tuberculosis   Rv0167   OG5_130961   Conserved integral membrane protein YrbE1A
M. tuberculosis   Rv0189c   OG5_128618   Probable dihydroxy-acid dehydratase IlvD (dad)
M. tuberculosis   Rv0205   OG5_131504   Probable conserved transmembrane protein
M. tuberculosis   Rv0208c   OG5_127179   Hypothetical methlytransferase (methylase)
M. tuberculosis   Rv0227c   OG5_237823   Probable conserved membrane protein
M. tuberculosis   Rv0228   OG5_176236   Probable integral membrane acyltransferase
M. tuberculosis   Rv0270   OG5_126609   Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA ...
M. tuberculosis   Rv0282   OG5_132590   ESX conserved component EccA3. ESX-3 type VII secretion system protein.
M. tuberculosis   Rv0283   OG5_237818   ESX conserved component EccB3. ESX-3 type VII secretion system protein. Possible ...
M. tuberculosis   Rv0285   OG5_204583   PE family protein PE5

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TDR Targets Development Release v6, Revision: 1403 (05.Dec.2018)
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