Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | beta-lactamase | 0.0086 | 0.1407 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0086 | 0.1407 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0194 | 0.1382 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0086 | 0.1407 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.0194 | 0.1382 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0086 | 0.1407 | 1 |
Onchocerca volvulus | 0.0086 | 0.1407 | 0.5 | |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0021 | 0.0194 | 0.5 |
Echinococcus granulosus | geminin | 0.0175 | 0.3075 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0086 | 0.1407 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0021 | 0.0194 | 0.1336 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0086 | 0.1407 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0194 | 0.1336 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0086 | 0.1407 | 0.4972 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.0194 | 0.1336 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0086 | 0.1407 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0086 | 0.1407 | 1 |
Echinococcus multilocularis | geminin | 0.0175 | 0.3075 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0086 | 0.1407 | 0.4564 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0316 | 0.569 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0086 | 0.1407 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0007 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.3075 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.3075 | 1 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0316 | 0.569 | 0.4984 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0007 | 0.0053 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0152 | 0.2634 | 0.2864 |
Onchocerca volvulus | 0.0086 | 0.1407 | 0.5 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0086 | 0.1407 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0000000011237 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Trypanosoma brucei | beta lactamase | 0.0152 | 0.2634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0021 | 0.0194 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0086 | 0.1407 | 0.4211 |
Schistosoma mansoni | DNA helicase recq1 | 0.0021 | 0.0194 | 0.061 |
Onchocerca volvulus | 0.0086 | 0.1407 | 0.5 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0086 | 0.1407 | 1 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0152 | 0.2634 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0086 | 0.1407 | 0.4211 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Brugia malayi | beta-lactamase | 0.0086 | 0.1407 | 1 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0021 | 0.0194 | 0.5 |
Schistosoma mansoni | DNA helicase recq5 | 0.0021 | 0.0194 | 0.061 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0086 | 0.1407 | 1 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0007 | 0.0381 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0086 | 0.1407 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0086 | 0.1407 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0194 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0086 | 0.1407 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0086 | 0.1407 | 0.4564 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0007 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1407 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.0194 | 0.1336 |
Leishmania major | hypothetical protein, conserved | 0.0086 | 0.1407 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0152 | 0.2634 | 0.1427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.