Detailed information for compound 1089932

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 517.662 | Formula: C30H39N5O3
  • H donors: 1 H acceptors: 3 LogP: 6.94 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)N1CCN(CC1(C)C)c1nc(cc(n1)C(=O)OC)Nc1cc(ccc1C)C(C)(C)C
  • InChi: 1S/C30H39N5O3/c1-20-9-10-21(29(2,3)4)17-24(20)31-26-18-25(27(36)38-8)32-28(33-26)34-15-16-35(30(5,6)19-34)22-11-13-23(37-7)14-12-22/h9-14,17-18H,15-16,19H2,1-8H3,(H,31,32,33)
  • InChiKey: SDNJLWMNEJNXRB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0039 0.0562 0.0811
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0599 0.2301
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.3666 0.3588
Schistosoma mansoni calpain C (C02 family) 0.0041 0.0599 0.0865
Echinococcus granulosus snurportin 1 0.0343 0.6921 0.6883
Schistosoma mansoni hypothetical protein 0.0041 0.0607 0.0877
Schistosoma mansoni hypothetical protein 0.0018 0.0122 0.0176
Plasmodium falciparum importin beta, putative 0.0032 0.0415 0.2709
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0303 0.3387
Trypanosoma brucei kinesin, putative 0.0029 0.0341 0.2228
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.3666 0.3588
Entamoeba histolytica Ran family GTPase 0.0024 0.0238 0.3912
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0122 0.0332
Echinococcus multilocularis calpain family protein 1, d 0.008 0.1413 0.1307
Toxoplasma gondii exonuclease III APE 0.004 0.058 0.3785
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.2565 0.3707
Echinococcus granulosus cathepsin b 0.0137 0.2602 0.2511
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.058 0.0464
Brugia malayi TAR-binding protein 0.0072 0.124 0.3383
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.3907
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0233
Trypanosoma cruzi kinesin, putative 0.0029 0.0341 0.1312
Schistosoma mansoni hypothetical protein 0.0343 0.6921 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0233
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.058 1
Loa Loa (eye worm) hypothetical protein 0.008 0.1413 0.2042
Brugia malayi hypothetical protein 0.0041 0.0607 0.1656
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0599 0.3907
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0238 0.0913
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0303 0.1979
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.058 0.5
Brugia malayi cathepsin B-like cysteine proteinase 0.0137 0.2602 0.7097
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0941 0.2566
Echinococcus granulosus calpain 7 C02 family 0.0041 0.0599 0.0483
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0343 0.6921 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0303 0.0827
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.1532 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0161 0.5
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.058 0.3785
Loa Loa (eye worm) hypothetical protein 0.0027 0.0303 0.0438
Loa Loa (eye worm) hypothetical protein 0.0108 0.2012 0.2907
Schistosoma mansoni hypothetical protein 0.0164 0.3167 0.4576
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0288 0.4195
Schistosoma mansoni tar DNA-binding protein 0.0072 0.124 0.1792
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0599 0.3907
Echinococcus multilocularis tar DNA binding protein 0.0072 0.124 0.1132
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.2301
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.058 1
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0122 0.0332
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0303 0.1979
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0303 0.1979
Echinococcus granulosus importin subunit beta 1 0.0032 0.0415 0.0297
Toxoplasma gondii LsmAD domain-containing protein 0.0086 0.1532 1
Brugia malayi RNA, U transporter 1 0.0091 0.1655 0.4513
Echinococcus granulosus tar DNA binding protein 0.0072 0.124 0.1132
Brugia malayi hypothetical protein 0.0055 0.0898 0.2449
Schistosoma mansoni hypothetical protein 0.0018 0.0122 0.0176
Leishmania major kinesin, putative 0.0029 0.0341 0.2228
Trypanosoma cruzi kinesin, putative 0.0029 0.0341 0.1312
Echinococcus multilocularis hypothetical protein 0.0041 0.0599 0.0483
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.124 0.3383
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0233
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0238 0.0117
Leishmania major GTP-binding protein, putative 0.0024 0.0238 0.155
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0161 0.0518
Onchocerca volvulus 0.0068 0.1156 1
Schistosoma mansoni calpain (C02 family) 0.0041 0.0599 0.0865
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0941 0.2566
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.3907
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.3666 0.3588
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0041 0.0599 0.2301
Echinococcus multilocularis calpain 5 0.0041 0.0599 0.0483
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.058 0.955
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0038 0.0545 0.0429
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.3907
Loa Loa (eye worm) hypothetical protein 0.0086 0.1532 0.2214
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0415 0.2709
Brugia malayi calpain 5 0.0029 0.0341 0.0931
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.058 0.3785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0303 0.373
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0303 0.3387
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0137 0.2602 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0045 0.0686 0.4479
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0238 0.0913
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.3666 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0045 0.0686 0.4479
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0303 0.0827
Loa Loa (eye worm) hypothetical protein 0.0032 0.0415 0.06
Trichomonas vaginalis ap endonuclease, putative 0.004 0.058 0.845
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.058 0.0464
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.3666 0.3588
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.2115 0.3056
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0113 0.2115 0.2018
Entamoeba histolytica hypothetical protein 0.0041 0.0607 1
Loa Loa (eye worm) TAR-binding protein 0.0072 0.124 0.1792
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0288 0.4195
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0288 0.1106
Loa Loa (eye worm) hypothetical protein 0.0018 0.0122 0.0176
Loa Loa (eye worm) calpain family protein 1 0.008 0.1413 0.2042
Echinococcus granulosus calpain 5 0.0041 0.0599 0.0483
Brugia malayi Importin beta-1 subunit 0.0032 0.0415 0.1132
Brugia malayi hypothetical protein 0.0086 0.1532 0.4179
Giardia lamblia Cathepsin B precursor 0.0045 0.0686 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0045 0.0686 0.0992
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0599 0.2301
Plasmodium vivax ataxin-2 like protein, putative 0.0086 0.1532 1
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.058 0.1582
Brugia malayi calpain family protein 1 0.0108 0.2012 0.5488
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.2301
Echinococcus multilocularis cathepsin b 0.0137 0.2602 0.2511
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.2301
Giardia lamblia Cathepsin B precursor 0.0045 0.0686 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.3666 0.5297
Entamoeba histolytica hypothetical protein 0.0026 0.0288 0.4741
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0238 0.155
Trichomonas vaginalis ap endonuclease, putative 0.004 0.058 0.845
Schistosoma mansoni Mername-AA248 (C02 family) 0.0041 0.0599 0.0865
Schistosoma mansoni tar DNA-binding protein 0.0072 0.124 0.1792
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.3666 0.5297
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.058 0.2229
Echinococcus granulosus cathepsin b 0.0137 0.2602 0.2511
Echinococcus multilocularis snurportin 1 0.0343 0.6921 0.6883
Schistosoma mansoni ap endonuclease 0.004 0.058 0.0838
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.058 0.3052
Echinococcus multilocularis neuropeptide s receptor 0.049 1 1
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0415 0.0297
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.058 0.0838
Echinococcus granulosus calpain 0.0041 0.0599 0.0483
Echinococcus granulosus geminin 0.0164 0.3167 0.3083
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0303 0.4993
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.3907
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0041 0.0599 0.2301
Echinococcus multilocularis calpain A 0.0113 0.2115 0.2018
Loa Loa (eye worm) hypothetical protein 0.0137 0.2602 0.376
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.058 0.3785
Brugia malayi calpain family protein 1 0.0108 0.2012 0.5488
Entamoeba histolytica hypothetical protein 0.0041 0.0607 1
Entamoeba histolytica protein kinase, putative 0.0029 0.0341 0.5621
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0238 0.155
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0599 0.3907
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0415 0.2709
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.3666 0.5297
Schistosoma mansoni hypothetical protein 0.0018 0.0122 0.0176
Echinococcus granulosus neuropeptide receptor A26 0.049 1 1
Leishmania major importin beta-1 subunit, putative 0.0026 0.0288 0.1879
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0137 0.2602 0.376
Schistosoma mansoni ap endonuclease 0.004 0.058 0.0838
Echinococcus multilocularis neuropeptide receptor A26 0.049 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0303 0.3387
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0045 0.0686 0.2637
Loa Loa (eye worm) hypothetical protein 0.0057 0.0941 0.1359
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0238 0.155
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0161 0.1054
Giardia lamblia Cathepsin B precursor 0.0045 0.0686 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0238 0.0343
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0599 0.2301
Plasmodium falciparum ataxin-2 like protein, putative 0.0086 0.1532 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0045 0.0686 1
Plasmodium vivax importin-beta 2, putative 0.0032 0.0415 0.185
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0303 0.4993
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0113 0.2115 0.2018
Schistosoma mansoni importin beta-1 0.0032 0.0415 0.06
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0137 0.2602 0.376
Loa Loa (eye worm) hypothetical protein 0.0039 0.0562 0.0811
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0599 0.0865
Loa Loa (eye worm) hypothetical protein 0.0027 0.0303 0.0438
Schistosoma mansoni tar DNA-binding protein 0.0072 0.124 0.1792
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0303 0.4993
Loa Loa (eye worm) hypothetical protein 0.0096 0.1755 0.2535
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0599 0.0865
Echinococcus multilocularis calpain 0.0041 0.0599 0.0483
Schistosoma mansoni hypothetical protein 0.0164 0.3167 0.4576
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.058 0.2229
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0303 0.3387
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.058 0.5
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.058 0.763
Toxoplasma gondii cathepsin B 0.0045 0.0686 0.4479
Trypanosoma brucei antigen, putative 0.0041 0.0599 0.3907
Schistosoma mansoni tar DNA-binding protein 0.0072 0.124 0.1792
Entamoeba histolytica hypothetical protein 0.0041 0.0607 1
Loa Loa (eye worm) calpain family protein 1 0.0108 0.2012 0.2907
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0562 0.1532
Loa Loa (eye worm) calpain 0.0041 0.0599 0.0865
Loa Loa (eye worm) hypothetical protein 0.0068 0.1156 0.167
Plasmodium vivax calpain, putative 0.0041 0.0599 0.319
Mycobacterium ulcerans hypothetical protein 0.0027 0.0303 0.3387
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0288 0.4195
Loa Loa (eye worm) RNA binding protein 0.0072 0.124 0.1792
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0303 0.5
Echinococcus granulosus calpain A 0.0041 0.0599 0.0483
Echinococcus granulosus calpain A 0.0113 0.2115 0.2018
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0303 0.3387
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.1532 0.5888
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0113 0.2115 0.3056
Echinococcus multilocularis cathepsin b 0.0137 0.2602 0.2511
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0607 0.0491
Schistosoma mansoni tar DNA-binding protein 0.0072 0.124 0.1792
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0137 0.2602 0.376
Entamoeba histolytica calpain large subunit domain III containing protein 0.0029 0.0341 0.5621
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0303 0.5
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0238 0.0117
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0122 0.0176
Schistosoma mansoni ran 0.0024 0.0238 0.0343
Echinococcus multilocularis calpain 7 (C02 family) 0.0041 0.0599 0.0483
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0041 0.0599 0.3907
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0233
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0941 0.1359
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0607 0.0877
Schistosoma mansoni hypothetical protein 0.0018 0.0122 0.0176
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.2565 0.3707
Brugia malayi RNA binding protein 0.0072 0.124 0.3383
Entamoeba histolytica hypothetical protein 0.0041 0.0607 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.124 0.1792
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0137 0.2602 0.376
Loa Loa (eye worm) cathepsin B 0.0045 0.0686 0.0992
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.3666 0.5297
Brugia malayi MH2 domain containing protein 0.0135 0.2565 0.6997
Trypanosoma brucei PAB1-binding protein , putative 0.0086 0.1532 1
Brugia malayi calpain 7 0.0041 0.0599 0.1633
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0599 0.2301
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0303 0.0827
Trichomonas vaginalis ran, putative 0.0024 0.0238 0.3461
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0041 0.0599 0.2301
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0108 0.2012 0.2907
Trypanosoma cruzi PAB1-binding protein , putative 0.0086 0.1532 0.5888
Loa Loa (eye worm) calpain 5 0.0029 0.0341 0.0493
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0303 0.373
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0233
Echinococcus multilocularis geminin 0.0164 0.3167 0.3083
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0303 0.3387
Leishmania major hypothetical protein, conserved 0.0086 0.1532 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0238 0.0555
Trypanosoma brucei calpain-like protein, putative 0.0041 0.0599 0.3907
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0238 0.0648
Schistosoma mansoni ran 0.0024 0.0238 0.0343
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0415 0.2709
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0303 0.3387
Schistosoma mansoni hypothetical protein 0.0038 0.0545 0.0788
Loa Loa (eye worm) hypothetical protein 0.0027 0.0303 0.0438
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0607 0.0491
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0038 0.0545 0.0429

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.